N-benzyl-4-methyl-N-((triisopropylsilyl)ethynyl)benzene sulfonamide

Base Information

• Chemical Name: N-benzyl-4-methyl-N-((triisopropylsilyl)ethynyl)benzene sulfonamide
• CAS No.: 683246-83-5
• Molecular Formula: C₂₅H₃₅NO₂SSi
• Molecular Weight: 441.71
• Mol file: 683246-83-5.mol

Synonyms:N-benzyl-4-methyl-N-((triisopropylsilyl)ethynyl)benzene sulfonamide

Chemical Property of N-benzyl-4-methyl-N-((triisopropylsilyl)ethynyl)benzene sulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-benzyl-4-methyl-N-((triisopropylsilyl)ethynyl)benzene sulfonamide

There total 6 articles about N-benzyl-4-methyl-N-((triisopropylsilyl)ethynyl)benzene sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

N-benzyl-p-toluenesulfonamide (1576-37-0) + 1-bromo-2-(triisopropylsilyl)acetylene (111409-79-1) → N-benzyl-4-methyl-N-((triisopropylsilyl)ethynyl)benzene sulfonamide (683246-83-5)

Guidance literature:

With potassium phosphate; 1,10-Phenanthroline; copper (II) sulfite; In toluene; at 60 - 65 ℃; for 32h;

DOI:10.1021/ol049827e

Reference yield: 69.0%

(3-bromoprop-2-ynyl)triisopropylsilane + N-benzyl-p-toluenesulfonamide (1576-37-0) → N-benzyl-4-methyl-N-((triisopropylsilyl)ethynyl)benzene sulfonamide (683246-83-5)

Guidance literature:

With iron(III) chloride hexahydrate; potassium carbonate; N,N`-dimethylethylenediamine; In toluene; at 90 ℃; for 12h;

DOI:10.1021/jo900595c

Reference yield: 68.0%

N-benzyl-p-toluenesulfonamide (1576-37-0) + (iodoethynyl)triisopropylsilane (160481-43-6) → N-benzyl-4-methyl-N-((triisopropylsilyl)ethynyl)benzene sulfonamide (683246-83-5)

Guidance literature:

With phenanthrene; potassium carbonate; copper(II) sulfate; In toluene; at 70 ℃; for 24h;

DOI:10.1016/j.jfluchem.2005.12.024

upstream raw materials:

N-benzyl-p-toluenesulfonamide

1-bromo-2-(triisopropylsilyl)acetylene

(iodoethynyl)triisopropylsilane

tris-iso-propylsilyl acetylene

Downstream raw materials:

N-benzyl-N-ethynyl-4-methyl-benzenesulfonamide

N-benzyl-p-toluenesulfonamide