160481-43-6

Basic information

• Product Name: (iodoethynyl)triisopropylsilane
• Synonyms: (iodoethynyl)triisopropylsilane
• CAS NO: 160481-43-6
• Molecular Formula: C₁₁H₂₁ISi
• Molecular Weight: 308.27441
• EINECS: -0
• Mol File: 160481-43-6.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 265.1±9.0 °C(Predicted)
• Appearance: /
• Density: 1.237±0.06 g/cm3(Predicted)
• CAS DataBase Reference: (iodoethynyl)triisopropylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: (iodoethynyl)triisopropylsilane(160481-43-6)
• EPA Substance Registry System: (iodoethynyl)triisopropylsilane(160481-43-6)

Safety Data

• Hazardous Substances Data: 160481-43-6(Hazardous Substances Data)

Usage

General Description

(Iodoethynyl)triisopropylsilane is a chemical compound with the molecular formula C11H21ISi. It is a colorless liquid that is highly reactive and is primarily used in organic synthesis as a building block for various functionalized silanes and silicon-based materials. The compound contains an iodoethynyl group, which contains both iodine and carbon triple bonds, making it a versatile reagent in chemical reactions. It is often used as a precursor in the preparation of organosilicon compounds, and its triisopropylsilane group provides stability and protection for the reactive iodine-ethynyl functionality. Overall, (iodoethynyl)triisopropylsilane plays a critical role in the development of advanced materials and in the synthesis of complex organic molecules.

Upstream product

• 89343-06-6 tris-iso-propylsilyl acetylene 

Downstream Products

• 1434615-85-6 1-phenyl-3-(p-tolyl)-5-(triisopropylsilyl)pent-4-yn-1-one 
• 1425052-44-3 2-propyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-5-(triisopropylsilyl)pent-4-ynamide 
• 1425052-60-3 (E)-5-(1,3-bis(triisopropylsilyl)prop-2-yn-1-ylidene)-3-propyl-1-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)pyrrolidin-2-one 
• 1403848-79-2 3-(1-(4-methoxyphenyl)-3-(triisopropylsilyl)prop-2-yn-1-yl)-1-methyl-1H-indole 
• 1335520-67-6 (3-(4-methoxyphenyl)penta-1,4-diyne-1,5-diyl)bis(triisopropylsilane) 
• 683246-83-5 N-benzyl-4-methyl-N-((triisopropylsilyl)ethynyl)benzene sulfonamide 

Relevant articles and documents

Synthesis method of 1-iodo-alkyne compound

The invention discloses a synthetic method of a 1-iodo-alkyne compound. The preparation method comprises the following steps: in an aerobic environment, mixing terminal alkyne, soluble inorganic iodized salt, sodium phenylsulfinate or a derivative thereof

Total Syntheses of Disorazoles A1 and B1 and Full Structural Elucidation of Disorazole B1

Described herein are the first total syntheses of naturally occurring antitumor agents disorazoles A1 and B1 and the full structural assignment of the latter. The syntheses were achieved through convergent strategies employing enantioselective constructions of the required building blocks, including a novel Sharpless epoxidation/enzymatic kinetic resolution of stannane-containing substrates that led selectively to both enantiomeric forms of an epoxy vinyl stannane, and a series of coupling reactions, including a Wittig reaction, a Suzuki coupling, a Stille coupling, a Yamaguchi esterification and a Yamaguchi macrolactonization.

Intramolecular palladium-catalyzed alkene carboalkynylation

Abstract Carbocycles are essential building blocks for the synthesis of natural and synthetic bioactive compounds. Herein, we report the first example of palladium-catalyzed intramolecular carboalkynylation of non-activated olefins. Using activated carbon