2-Hydroxy-5-iodo-4-methylbenzoic acid

Base Information

Chemical Name:2-Hydroxy-5-iodo-4-methylbenzoic acid
CAS No.:850146-83-7
Molecular Formula:C8H7 I O3
Molecular Weight:278.04385
Hs Code.:2918290000
DSSTox Substance ID:DTXSID90460614
Nikkaji Number:J3.132.413K
Wikidata:Q82284724
Mol file:850146-83-7.mol

Synonyms:2-hydroxy-5-iodo-4-methylbenzoic acid;850146-83-7;DTXSID90460614;MFCD09033136;AKOS015965090;AC-1526;A856437

Suppliers and Price of 2-Hydroxy-5-iodo-4-methylbenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-HYDROXY-5-IODO-4-METHYLBENZOIC ACID 95.00%
5G
$ 1370.41

Alichem
2-Hydroxy-5-iodo-4-methylbenzoicacid
5g
$ 1093.92

Total 9 raw suppliers

Chemical Property of 2-Hydroxy-5-iodo-4-methylbenzoic acid

Chemical Property:

Vapor Pressure:9.75E-07mmHg at 25°C
Refractive Index:1.686
Boiling Point:388.7°C at 760 mmHg
Flash Point:188.9°C
PSA：57.53000
Density:2.004g/cm³
LogP:2.00340
Storage Temp.:2-8°C
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:277.94399
Heavy Atom Count:12
Complexity:183

Purity/Quality:

97% ^*data from raw suppliers

2-HYDROXY-5-IODO-4-METHYLBENZOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1I)C(=O)O)O

Technology Process of 2-Hydroxy-5-iodo-4-methylbenzoic acid

There total 3 articles about 2-Hydroxy-5-iodo-4-methylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 50-85-1
2-hydroxy-p-toluic acid

: 850146-83-7
2-hydroxy-5-iodo-4-methylbenzoic acid

Guidance literature:: With potassium 4-iodylbenzene-1-sulfonate; iodine; In water; acetonitrile; at 25 ℃; for 12h;
DOI:10.1002/ejoc.201201064

Reference yield:

: 96-98-0
4-methyl-3-nitrobenzoic acid

: 850146-83-7
2-hydroxy-5-iodo-4-methylbenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: concentrated sulfuric acid / Electrolysis

2: durch Austausch von NH₂ gegen Jod nach Sandmeyer

With sulfuric acid;