2-(7-METHOXYINDOL-1H-3-YL)ACETIC ACID

Base Information

• Chemical Name: 2-(7-METHOXYINDOL-1H-3-YL)ACETIC ACID
• CAS No.: 850008-37-6
• Molecular Formula: C11H11 N O3
• Molecular Weight: 205.21
• Hs Code.: 2933990090
• Mol file: 850008-37-6.mol

Synonyms:7-METHOXYINDOLE-3-ACETIC ACID;2-(7-METHOXYINDOL-1H-3-YL)ACETIC ACID

Chemical Property of 2-(7-METHOXYINDOL-1H-3-YL)ACETIC ACID

Chemical Property:

• PSA: 62.32000
• LogP: 1.80360

Purity/Quality:

99% ^*data from raw suppliers

2-(7-Methoxy-1H-indol-3-yl)aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(7-METHOXYINDOL-1H-3-YL)ACETIC ACID

There total 6 articles about 2-(7-METHOXYINDOL-1H-3-YL)ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C12H13NO3 (1067080-51-6) → 7-methoxyindoleacetic acid (850008-37-6)

Guidance literature:

With potassium hydroxide; In tetrahydrofuran; water; at 20 ℃;

DOI:10.1016/j.phytochem.2007.04.030

Reference yield:

7-methoxy-1H-indole (3189-22-8) → 7-methoxyindoleacetic acid (850008-37-6)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrahydrofuran / 2 h / 0 °C

2: triethylamine / tetrahydrofuran / 4 h / 20 °C

3: 96 percent / NaH₂PO₂*H₂O / palladium on activated charcoal / dioxane; H₂O / 48 h / 20 °C

4: 100 percent / KOH / tetrahydrofuran; H₂O / 20 °C

With potassium hydroxide; sodium hypophosphite; triethylamine; isobutyric Acid; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; water;

DOI:10.1016/j.phytochem.2007.04.030

Reference yield:

7-methoxyindole-3-glyoxyl chloride (50656-47-8) → 7-methoxyindoleacetic acid (850008-37-6)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / tetrahydrofuran / 4 h / 20 °C

2: 96 percent / NaH₂PO₂*H₂O / palladium on activated charcoal / dioxane; H₂O / 48 h / 20 °C

3: 100 percent / KOH / tetrahydrofuran; H₂O / 20 °C

With potassium hydroxide; sodium hypophosphite; triethylamine; isobutyric Acid; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; water;

DOI:10.1016/j.phytochem.2007.04.030

upstream raw materials:

C₁₂H₁₃NO₃

7-methoxy-1H-indole

7-methoxyindole-3-glyoxyl chloride

(7-Methoxy-1H-indol-3-yl)-oxo-acetic acid methyl ester

Downstream raw materials:

C₂₄H₂₈O₄N₂

Refernces