1-(5-O-triphenylmethyl-2,3-O-isopropylidene-α-D-ribofuranosyl)-5,6-dimethylbenzimidazole

Base Information

• Chemical Name: 1-(5-O-triphenylmethyl-2,3-O-isopropylidene-α-D-ribofuranosyl)-5,6-dimethylbenzimidazole
• CAS No.: 84396-42-9
• Molecular Formula: C₃₆H₃₆N₂O₄
• Molecular Weight: 560.693
• Mol file: 84396-42-9.mol

Synonyms:1-(5-O-triphenylmethyl-2,3-O-isopropylidene-α-D-ribofuranosyl)-5,6-dimethylbenzimidazole

Chemical Property of 1-(5-O-triphenylmethyl-2,3-O-isopropylidene-α-D-ribofuranosyl)-5,6-dimethylbenzimidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(5-O-triphenylmethyl-2,3-O-isopropylidene-α-D-ribofuranosyl)-5,6-dimethylbenzimidazole

There total 1 articles about 1-(5-O-triphenylmethyl-2,3-O-isopropylidene-α-D-ribofuranosyl)-5,6-dimethylbenzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3-O-isopropylidene-5-O-trityl-D-ribofuranose (54503-64-9,54503-65-0) + 5,6-dimethyl-1-(trimethylsilyl)-1H-benzimidazole (91275-64-8) → 1-(5-O-triphenylmethyl-2,3-O-isopropylidene-α-D-ribofuranosyl)-5,6-dimethylbenzimidazole (84396-42-9) + 1-(5-O-triphenylmethyl-2,3-O-isopropylidene-β-D-ribofuranosyl)-5,6-dimethylbenzimidazole (84396-43-0)

Guidance literature:

With 2-fluoro-methylpyridinium tosylate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at -30 - 0 ℃;

DOI:10.1016/j.tetlet.2005.09.180

Reference yield: 98.0%

1-(5-O-triphenylmethyl-2,3-O-isopropylidene-α-D-ribofuranosyl)-5,6-dimethylbenzimidazole (84396-42-9) → 5,6-dimethyl-α-D-ribofuranosylbenzimidazole (132-13-8)

Guidance literature:

With carbon tetrabromide; In methanol; at 20 ℃; for 1h; Photolysis;

DOI:10.1016/j.tetlet.2005.09.180

Reference yield:

1-(5-O-triphenylmethyl-2,3-O-isopropylidene-α-D-ribofuranosyl)-5,6-dimethylbenzimidazole (84396-42-9) → 5,6-Dimethyl-1-β-D-ribofuranosyl-benzimidazol (13082-84-3) + 5,6-dimethyl-α-D-ribofuranosylbenzimidazole (132-13-8)

Guidance literature:

With carbon tetrabromide; In methanol; for 12h; Heating;

DOI:10.1016/j.tetlet.2005.09.180

upstream raw materials:

2,3-O-isopropylidene-5-O-trityl-D-ribofuranose

5,6-dimethyl-1-(trimethylsilyl)-1H-benzimidazole

Downstream raw materials:

5,6-Dimethyl-1-β-D-ribofuranosyl-benzimidazol

5,6-dimethyl-α-D-ribofuranosylbenzimidazole