Technology Process of C25H29ClN6O3S
There total 7 articles about C25H29ClN6O3S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C22H31N5O2;
With
hydrogenchloride;
In
1,4-dioxane;
for 0.5h;
5-chloro-2-(methylsulfonamido)benzoic acid;
With
triethylamine; HATU;
In
N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium bis(trimethylsilyl)amide / tetrahydrofuran / 0.42 h / -78 - -20 °C / Inert atmosphere
1.2: 3.08 h / -78 - -45 °C
1.3: -78 - 20 °C
2.1: hydrazinium monoacetate / ethanol / 16 h / 20 °C
3.1: acetic acid / 100 °C
4.1: 2,6-dimethylpyridine; trichlorophosphate / 0.5 h / 140 °C
5.1: 0.5 h / 20 °C
6.1: hydrogenchloride / 1,4-dioxane / 0.5 h
With
2,6-dimethylpyridine; hydrogenchloride; sodium bis(trimethylsilyl)amide; hydrazinium monoacetate; acetic acid; trichlorophosphate;
In
tetrahydrofuran; 1,4-dioxane; ethanol;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium bis(trimethylsilyl)amide / tetrahydrofuran; hexanes / -78 - -40 °C
1.2: -78 - -40 °C
1.3: -78 - 20 °C
2.1: hydrazinium monoacetate / ethanol / 16 h / 20 °C
3.1: acetic acid / 100 °C
4.1: 2,6-dimethylpyridine; trichlorophosphate / 0.5 h / 140 °C
5.1: 0.5 h / 20 °C
6.1: hydrogenchloride / 1,4-dioxane / 0.5 h
With
2,6-dimethylpyridine; hydrogenchloride; sodium bis(trimethylsilyl)amide; hydrazinium monoacetate; acetic acid; trichlorophosphate;
In
tetrahydrofuran; 1,4-dioxane; hexanes; ethanol;
