3,7-dibenzyl-2,4,6,8-tetraoxo-3,7-diazabicyclo[3.3.1]nonane

Base Information

• Chemical Name: 3,7-dibenzyl-2,4,6,8-tetraoxo-3,7-diazabicyclo[3.3.1]nonane
• CAS No.: 1071433-49-2
• Molecular Formula: C₂₁H₁₈N₂O₄
• Molecular Weight: 362.385
• Mol file: 1071433-49-2.mol

Synonyms:3,7-dibenzyl-2,4,6,8-tetraoxo-3,7-diazabicyclo[3.3.1]nonane

Chemical Property of 3,7-dibenzyl-2,4,6,8-tetraoxo-3,7-diazabicyclo[3.3.1]nonane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 3,7-dibenzyl-2,4,6,8-tetraoxo-3,7-diazabicyclo[3.3.1]nonane

There total 1 articles about 3,7-dibenzyl-2,4,6,8-tetraoxo-3,7-diazabicyclo[3.3.1]nonane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2,4,6,8-tetraoxo-3,7-diazabicyclo[3.3.1]nonane (4889-98-9) + benzyl bromide (100-39-0) → 3,7-dibenzyl-2,4,6,8-tetraoxo-3,7-diazabicyclo[3.3.1]nonane (1071433-49-2)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃;

DOI:10.1021/jo8013512

Reference yield: 50.0%

3,7-dibenzyl-2,4,6,8-tetraoxo-3,7-diazabicyclo[3.3.1]nonane (1071433-49-2) → (+/-)-(1R,2R,5R,6R)-3,7-dibenzyl-2,6-dihydroxy-4,8-dioxo-3,7-diazabicyclo[3.3.1]nonane

Guidance literature:

With lithium triethylborohydride; In dichloromethane; at -78 ℃; for 2h;

DOI:10.1021/jo8013512

Reference yield: 15.0%

3,7-dibenzyl-2,4,6,8-tetraoxo-3,7-diazabicyclo[3.3.1]nonane (1071433-49-2) → (1S,2S,5R)-3,7-dibenzyl-2-hydroxy-4,6,8-trioxo-3,7-diazabicyclo[3.3.1]nonane + (1R,2S,5S)-3,7-dibenzyl-2-hydroxy-4,6,8-trioxo-3,7-diazabicyclo[3.3.1]nonane + (1R,2R,5S)-3,7-dibenzyl-2-hydroxy-4,6,8-trioxo-3,7-diazabicyclo[3.3.1]nonane (1071434-21-3) + (2R,8R)-3,7-dibenzyl-2,8-dihydroxy-4,6-dioxo-3,7-diazabicyclo[3.3.1]nonane

Guidance literature:

With borane-THF; (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole; In tetrahydrofuran; toluene; at 0 ℃; for 2.5h;

DOI:10.1021/jo8013512

upstream raw materials:

2,4,6,8-tetraoxo-3,7-diazabicyclo[3.3.1]nonane

benzyl bromide

Downstream raw materials:

(1R,2R,5S)-3,7-dibenzyl-2-hydroxy-4,6,8-trioxo-3,7-diazabicyclo[3.3.1]nonane

(1S,5R,6S)-6-allyl-3,7-dibenzyl-2,4,8-trioxo-3,7-diazabicyclo[3.3.1]nonane