3-(3-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-n-propylphenoxy)benzyl)-5-(4-(1-methylethoxy)phenyl)-5-methylimidazolidine-2,4-dione

Base Information

Chemical Name:3-(3-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-n-propylphenoxy)benzyl)-5-(4-(1-methylethoxy)phenyl)-5-methylimidazolidine-2,4-dione
CAS No.:1198164-25-8
Molecular Formula:C₃₂H₃₂F₆N₂O₅
Molecular Weight:638.607
Hs Code.:

Synonyms:3-(3-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-n-propylphenoxy)benzyl)-5-(4-(1-methylethoxy)phenyl)-5-methylimidazolidine-2,4-dione

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Chemical Property of 3-(3-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-n-propylphenoxy)benzyl)-5-(4-(1-methylethoxy)phenyl)-5-methylimidazolidine-2,4-dione

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Technology Process of 3-(3-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-n-propylphenoxy)benzyl)-5-(4-(1-methylethoxy)phenyl)-5-methylimidazolidine-2,4-dione

There total 7 articles about 3-(3-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-n-propylphenoxy)benzyl)-5-(4-(1-methylethoxy)phenyl)-5-methylimidazolidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₄H₃₆F₆N₂O₆

: 1198164-25-8
3-(3-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-n-propylphenoxy)benzyl)-5-(4-(1-methylethoxy)phenyl)-5-methylimidazolidine-2,4-dione

Guidance literature:: With hydrogenchloride; In ethyl acetate; at 0 - 20 ℃; for 1h;
DOI:10.1016/j.bmc.2016.05.048

Reference yield:

: 1198164-16-7
(3-(4-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-2-n-propylphenoxy)phenyl)methanol

: 1198164-25-8
3-(3-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-n-propylphenoxy)benzyl)-5-(4-(1-methylethoxy)phenyl)-5-methylimidazolidine-2,4-dione

Guidance literature:: Multi-step reaction with 3 steps

1: triphenylphosphine; carbon tetrabromide / dichloromethane / 0 - 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 20 °C

3: hydrogenchloride / ethyl acetate / 1 h / 0 - 20 °C

With hydrogenchloride; carbon tetrabromide; potassium carbonate; triphenylphosphine; In dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2016.05.048

Reference yield:

: 1198164-15-6
1-(3-(bromomethyl)phenoxy)-4-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-2-n-propylbenzene

: 1198164-25-8
3-(3-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-n-propylphenoxy)benzyl)-5-(4-(1-methylethoxy)phenyl)-5-methylimidazolidine-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 20 °C

2: hydrogenchloride / ethyl acetate / 1 h / 0 - 20 °C

With hydrogenchloride; potassium carbonate; In ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2016.05.048