(S)-2-(4-fluorophenyl)-1-(4-nitrophenylsulfonyl)-2,5-dihydro-1H-pyrrole

Base Information

Chemical Name:(S)-2-(4-fluorophenyl)-1-(4-nitrophenylsulfonyl)-2,5-dihydro-1H-pyrrole
CAS No.:1374877-93-6
Molecular Formula:C₁₆H₁₃FN₂O₄S
Molecular Weight:348.355
Hs Code.:

Synonyms:(S)-2-(4-fluorophenyl)-1-(4-nitrophenylsulfonyl)-2,5-dihydro-1H-pyrrole

Suppliers and Price of (S)-2-(4-fluorophenyl)-1-(4-nitrophenylsulfonyl)-2,5-dihydro-1H-pyrrole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-2-(4-fluorophenyl)-1-(4-nitrophenylsulfonyl)-2,5-dihydro-1H-pyrrole

Chemical Property:

Purity/Quality:

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MSDS Files:: SDS file from LookChem

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Technology Process of (S)-2-(4-fluorophenyl)-1-(4-nitrophenylsulfonyl)-2,5-dihydro-1H-pyrrole

There total 1 articles about (S)-2-(4-fluorophenyl)-1-(4-nitrophenylsulfonyl)-2,5-dihydro-1H-pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: C₁₆H₁₄BrFN₂O₄S

: 1374877-93-6
(S)-2-(4-fluorophenyl)-1-(4-nitrophenylsulfonyl)-2,5-dihydro-1H-pyrrole

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; optical yield given as %ee; enantioselective reaction; Reflux;
DOI:10.1039/c2ob25327e

Reference yield: 74.0%

: 1374877-93-6
(S)-2-(4-fluorophenyl)-1-(4-nitrophenylsulfonyl)-2,5-dihydro-1H-pyrrole

: 1374877-94-7
(S)-2-(4-fluorophenyl)-2,5-dihydro-1H-pyrrole

Guidance literature:: With thiophenol; lithium hydroxide; at 25 ℃; optical yield given as %ee;
DOI:10.1039/c2ob25327e

Reference yield:

: 1374877-93-6
(S)-2-(4-fluorophenyl)-1-(4-nitrophenylsulfonyl)-2,5-dihydro-1H-pyrrole

: 298690-90-1
(S)-2-(4-fluorophenyl)pyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: thiophenol; lithium hydroxide / 25 °C

2: palladium on activated charcoal; hydrogen / ethanol / Inert atmosphere

With palladium on activated charcoal; hydrogen; thiophenol; lithium hydroxide; In ethanol;
DOI:10.1039/c2ob25327e