(S)-2-(4-Fluorophenyl)pyrrolidine

Base Information

Chemical Name:(S)-2-(4-Fluorophenyl)pyrrolidine
CAS No.:298690-90-1
Molecular Formula:C10H12FN
Molecular Weight:165.21
Hs Code.:2933998090
DSSTox Substance ID:DTXSID80427458
Nikkaji Number:J3.066.715H
Wikidata:Q72476415
Mol file:298690-90-1.mol

Synonyms:(S)-2-(4-Fluorophenyl)pyrrolidine;298690-90-1;(2S)-2-(4-fluorophenyl)pyrrolidine;Pyrrolidine, 2-(4-fluorophenyl)-, (2S)-;(S)-2-(4-fluorophenyl) pyrrolidine;SCHEMBL169110;DTXSID80427458;AM9275;MFCD06761856;AKOS015933161;(2S)-2-(4-fluorophenyl)-pyrrolidine;(S)-2-(4-fluoro-phenyl)-pyrrolidine;CS-W021158;DS-6362;(2S)-2alpha-(4-Fluorophenyl)pyrrolidine;AC-30323;A876368

Suppliers and Price of (S)-2-(4-Fluorophenyl)pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-2-(4-Fluorophenyl)pyrrolidine
50mg
$ 220.00

TRC
(S)-2-(4-Fluorophenyl)pyrrolidine
5mg
$ 45.00

SynQuest Laboratories
(S)-2-(4-Fluorophenyl)pyrrolidine 98%
1 g
$ 946.00

Labseeker
(S)-2-(4-fluorophenyl)pyrrolidine 95
1g
$ 750.00

Crysdot
(S)-2-(4-Fluorophenyl)pyrrolidine 98%
5g
$ 1829.00

Crysdot
(S)-2-(4-Fluorophenyl)pyrrolidine 98%
250mg
$ 249.00

Crysdot
(S)-2-(4-Fluorophenyl)pyrrolidine 98%
1g
$ 621.00

Chemenu
(S)-2-(4-Fluorophenyl)pyrrolidine 95+%
1g
$ 587.00

Apolloscientific
(S)-2-(4-Fluorophenyl)pyrrolidine 98%
1g
$ 857.00

Apolloscientific
(S)-2-(4-Fluorophenyl)pyrrolidine 98%
250mg
$ 344.00

Total 34 raw suppliers

Chemical Property of (S)-2-(4-Fluorophenyl)pyrrolidine

Chemical Property:

Vapor Pressure:0.0497mmHg at 25°C
Refractive Index:1.515
Boiling Point:235.5 °C at 760 mmHg
PKA:9.76±0.10(Predicted)
Flash Point:96.3 °C
PSA：12.03000
Density:1.078 g/cm³
LogP:2.57900
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:165.095377549
Heavy Atom Count:12
Complexity:141

Purity/Quality:

99%, ^*data from raw suppliers

(S)-2-(4-Fluorophenyl)pyrrolidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(NC1)C2=CC=C(C=C2)F
Isomeric SMILES:C1C[C@H](NC1)C2=CC=C(C=C2)F

Technology Process of (S)-2-(4-Fluorophenyl)pyrrolidine

There total 7 articles about (S)-2-(4-Fluorophenyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1374877-94-7
(S)-2-(4-fluorophenyl)-2,5-dihydro-1H-pyrrole

: 298690-90-1
(S)-2-(4-fluorophenyl)pyrrolidine

Guidance literature:: With palladium on activated charcoal; hydrogen; In ethanol; optical yield given as %ee; Inert atmosphere;
DOI:10.1039/c2ob25327e

Reference yield: 78.4%

: 22217-86-3
2-(4-fluorophenyl)-Δ¹-pyrrolidine

: 298690-90-1
(S)-2-(4-fluorophenyl)pyrrolidine

Guidance literature:: With hydrogenchloride; 2,3,4,5,6-pentahydroxy-hexanal; nicotinamide adenine dinucleotide phosphate; In aq. phosphate buffer; water; dimethyl sulfoxide; at 30 ℃; for 24h; pH=7; enantioselective reaction; Enzymatic reaction;
DOI:10.1021/acs.orglett.0c00802

Reference yield:

: tert-butyl (4-(4-fluorophenyl)-4-oxobutyl)carbamate

: 298690-90-1
(S)-2-(4-fluorophenyl)pyrrolidine

: 298690-89-8
(R)-2-(4-fluorophenyl)pyrrolidine

Guidance literature:: tert-butyl (4-(4-fluorophenyl)-4-oxobutyl)carbamate; With trifluoroacetic acid; In dichloromethane; for 3h; Inert atmosphere; Schlenk technique;

With 1,4-diaza-bicyclo[2.2.2]octane; titanium(IV) isopropylate; bis(1,5-cyclooctadiene)diiridium(I) dichloride; (2R)-1-[(1R)-1-[bis(1,1-dimethylethyl)phosphino]ethyl]-2-[bis[4-(trifluoromethyl)phenyl]phosphino]ferrocene; hydrogen; potassium iodide; In tetrahydrofuran; toluene; at 50 ℃; for 13h; under 38002.6 Torr; Overall yield = 94 percent; Overall yield = 31 mg; enantioselective reaction; Autoclave;
DOI:10.1055/s-0037-1611533