(4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-[(3-chlorophenyl)amino]imidazoline hydrochloride

Base Information

Chemical Name:(4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-[(3-chlorophenyl)amino]imidazoline hydrochloride
CAS No.:1269487-68-4
Molecular Formula:C₁₉H₂₁ClN₄O₂*ClH
Molecular Weight:409.315
Hs Code.:

Synonyms:(4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-[(3-chlorophenyl)amino]imidazoline hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-[(3-chlorophenyl)amino]imidazoline hydrochloride

Chemical Property:

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Technology Process of (4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-[(3-chlorophenyl)amino]imidazoline hydrochloride

There total 4 articles about (4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-[(3-chlorophenyl)amino]imidazoline hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1269603-78-2
(4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-[(3-chlorophenyl)amino]imidazoline

: 1269487-68-4
(4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-[(3-chlorophenyl)amino]imidazoline hydrochloride

Guidance literature:: With hydrogenchloride; In methanol;
DOI:10.1016/j.bmc.2010.11.039

Reference yield:

: 21258-04-8
N-benzoyl-N′-(3-chlorophenyl)thiourea

: 1269487-68-4
(4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-[(3-chlorophenyl)amino]imidazoline hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: water; sodium hydroxide / 0.67 h / 90 °C

2.1: methanol / 3 h / Reflux

3.1: pentan-1-ol / 24 h / Reflux

3.2: pH 12

4.1: hydrogenchloride / methanol

With hydrogenchloride; water; sodium hydroxide; In methanol; pentan-1-ol;
DOI:10.1016/j.bmc.2010.11.039

Reference yield:

: 4947-89-1
1-(3-chlorophenyl)-2-thiourea

: 1269487-68-4
(4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-[(3-chlorophenyl)amino]imidazoline hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: methanol / 3 h / Reflux

2.1: pentan-1-ol / 24 h / Reflux

2.2: pH 12

3.1: hydrogenchloride / methanol

With hydrogenchloride; In methanol; pentan-1-ol;
DOI:10.1016/j.bmc.2010.11.039