3-(tert-butyldimethylsilyloxy)-2-[2,2-bis(phenylsulfonyl)-4-pentynyl]-4H-4-pyranone

Base Information

Chemical Name:3-(tert-butyldimethylsilyloxy)-2-[2,2-bis(phenylsulfonyl)-4-pentynyl]-4H-4-pyranone
CAS No.:270253-52-6
Molecular Formula:C₂₈H₃₂O₇S₂Si
Molecular Weight:572.775
Hs Code.:

Synonyms:3-(tert-butyldimethylsilyloxy)-2-[2,2-bis(phenylsulfonyl)-4-pentynyl]-4H-4-pyranone

Suppliers and Price of 3-(tert-butyldimethylsilyloxy)-2-[2,2-bis(phenylsulfonyl)-4-pentynyl]-4H-4-pyranone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(tert-butyldimethylsilyloxy)-2-[2,2-bis(phenylsulfonyl)-4-pentynyl]-4H-4-pyranone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(tert-butyldimethylsilyloxy)-2-[2,2-bis(phenylsulfonyl)-4-pentynyl]-4H-4-pyranone

There total 2 articles about 3-(tert-butyldimethylsilyloxy)-2-[2,2-bis(phenylsulfonyl)-4-pentynyl]-4H-4-pyranone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 151993-29-2
1-(1-(phenylsulfonyl)but-3-ynylsulfonyl)benzene

: 152547-42-7
2-(bromomethyl)-3-((tert-butyldimethylsilyl)oxy)-4H-pyran-4-one

: 270253-52-6
3-(tert-butyldimethylsilyloxy)-2-[2,2-bis(phenylsulfonyl)-4-pentynyl]-4H-4-pyranone

Guidance literature:: With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In dichloromethane; water; at 20 ℃; for 12h;
DOI:10.1021/jo9917893

Reference yield:

: 3406-02-8
bis(phenylsulfonyl)methane

: 270253-52-6
3-(tert-butyldimethylsilyloxy)-2-[2,2-bis(phenylsulfonyl)-4-pentynyl]-4H-4-pyranone

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH / dimethylformamide / 20 - 70 °C

1.2: 91 percent / dimethylformamide; toluene / 0.08 h / 70 °C

2.1: 57 percent / NaOH; n-Bu₄NHSO₄ / CH₂Cl₂; H₂O / 12 h / 20 °C

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; sodium hydride; In dichloromethane; water; N,N-dimethyl-formamide; 1.1: Metallation / 1.2: Alkylation / 2.1: Substitution;
DOI:10.1021/jo9917893