Technology Process of 3-Bromo-7-methoxy-1-naphthonitrile
There total 6 articles about 3-Bromo-7-methoxy-1-naphthonitrile which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogenchloride; acetic acid; tin(ll) chloride;
In
water;
at 100 ℃;
for 6h;
- Guidance literature:
-
1-cyano-7-methoxynaphthalene;
With
bromine;
In
acetic acid;
at 45 ℃;
Reflux;
With
hydrogenchloride; tin(IV) tetrachloride dihydrate;
In
water; acetic acid;
at 100 ℃;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: ZnI2 / benzene / 20 °C
1.2: POCl3; pyridine / benzene / 6 h / Heating
2.1: p-cymene / Pd/C / Heating
3.1: 0.88 g / C6H5N*HCl / 2 h / 190 °C
4.1: Br2; acetic acid / 6 h / 100 °C
4.2: aq. HCl; SnCl2 / 1 h / 100 °C
5.1: 2.41 g / K2CO3 / acetone / Heating
With
4-methylisopropylbenzene; C6H5N*HCl; bromine; potassium carbonate; acetic acid; zinc(II) iodide;
palladium on activated charcoal;
In
acetone; benzene;
DOI:10.1021/jm058173s
