2-methyl-5-(1-methyl-ethenyl)-1-tertbutyl-diphenylsiloxycyclohexene

Base Information

• Chemical Name: 2-methyl-5-(1-methyl-ethenyl)-1-tertbutyl-diphenylsiloxycyclohexene
• CAS No.: 107957-81-3
• Molecular Formula: C₂₆H₃₄OSi
• Molecular Weight: 390.641
• Mol file: 107957-81-3.mol

Synonyms:2-methyl-5-(1-methyl-ethenyl)-1-tertbutyl-diphenylsiloxycyclohexene

Chemical Property of 2-methyl-5-(1-methyl-ethenyl)-1-tertbutyl-diphenylsiloxycyclohexene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 2-methyl-5-(1-methyl-ethenyl)-1-tertbutyl-diphenylsiloxycyclohexene

There total 1 articles about 2-methyl-5-(1-methyl-ethenyl)-1-tertbutyl-diphenylsiloxycyclohexene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(5S)-2-methyl-5-(prop-1-en-2-yl)cyclohexan-1-one (201012-68-2) + tert-butylchlorodiphenylsilane (58479-61-1) → 2-methyl-5-(1-methyl-ethenyl)-1-tertbutyl-diphenylsiloxycyclohexene (107957-81-3)

Guidance literature:

DOI:10.1016/S0040-4020(01)82058-5

Reference yield:

2-methyl-5-(1-methyl-ethenyl)-1-tertbutyl-diphenylsiloxycyclohexene (107957-81-3) → eudesma-4,11-dien-3-one (473-08-5)

Guidance literature:

Multi-step reaction with 2 steps

1: BF₃*Et₂O / nitromethane / 1 h / -20 °C

2: 78 percent / KOH / ethanol / 25 °C

With potassium hydroxide; boron trifluoride diethyl etherate; In nitromethane; ethanol;

DOI:10.1016/S0040-4020(01)82058-5

Reference yield:

3-methoxy-2-pentene-1-ol (107957-68-6) + 2-methyl-5-(1-methyl-ethenyl)-1-tertbutyl-diphenylsiloxycyclohexene (107957-81-3) → <1S,4R>-1-methyl-1-(3-pentanone)-4-isopropenyl-2-oxocyclohexane (108032-82-2) + (2R,5R)-2-methyl-2-(3-oxopentyl)-5-isopropenylcyclohexan-1-one (107957-82-4)

Guidance literature:

With boron trifluoride diethyl etherate; In nitromethane; at -20 ℃; for 1h; Yield given;

DOI:10.1016/S0040-4020(01)82058-5

upstream raw materials:

(5S)-2-methyl-5-(prop-1-en-2-yl)cyclohexan-1-one

tert-butylchlorodiphenylsilane

Downstream raw materials:

<1S,4R>-1-methyl-1-(3-pentanone)-4-isopropenyl-2-oxocyclohexane

(2R,5R)-2-methyl-2-(3-oxopentyl)-5-isopropenylcyclohexan-1-one

eudesma-4,11-dien-3-one