201012-68-2

Basic information

• Product Name: (5S)-2-methyl-5-(prop-1-en-2-yl)cyclohexan-1-one
• Synonyms: (5S)-2-methyl-5-(prop-1-en-2-yl)cyclohexan-1-one
• CAS NO: 201012-68-2
• Molecular Weight: 152.236
• Mol File: 201012-68-2.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: (5S)-2-methyl-5-(prop-1-en-2-yl)cyclohexan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5S)-2-methyl-5-(prop-1-en-2-yl)cyclohexan-1-one(201012-68-2)
• EPA Substance Registry System: (5S)-2-methyl-5-(prop-1-en-2-yl)cyclohexan-1-one(201012-68-2)

Safety Data

• Hazardous Substances Data: 201012-68-2(Hazardous Substances Data)

Upstream product

• 2244-16-8 (S)-p-mentha-6,8-dien-2-one 
• 70122-89-3 tert-butyl allyl carbonate 
• 35466-83-2 allyl methyl carbonate 
• 78-94-4 methyl vinyl ketone 
• 160837-29-6 (5S)-5-isopropenyl-2-methyl-1-trimethylsilyloxy-cyclohex-1-ene 
• 1629-58-9 4-penten-3-one 

Downstream Products

• 1259403-91-2 (5S)-N,2-dimethyl-5-(prop-1-en-2-yl)cyclohexan-1-amine 
• 1309660-00-1 1-[(5S)-2-methyl-5-(methylethyl)cyclohex-1-enyloxy]-1,1-dimethyl-1-silaethane 
• 1309659-99-1 (2S,5S)-2-methyl-5-(methylethyl)-2-prop-2-enylcyclohexan-1-one 
• 1309660-01-2 (2R,5S)-2-methyl-5-(methylethyl)-2-prop-2-enylcyclohexan-1-one 
• 160168-89-8 (5S)-2-methyl-5-(methylethyl)cyclohexan-1-one 
• 468-76-8 Cassaine 
• 1443670-86-7 (5R)-2-methyl-5-((E)-1-nitroprop-1-en-2-yl)cyclohexanone 
• 1004960-23-9 C₁₈H₂₅N 
• 215960-01-3 C₁₈H₂₅N 
• 108032-82-2 <1S,4R>-1-methyl-1-(3-pentanone)-4-isopropenyl-2-oxocyclohexane 
• 473-08-5 eudesma-4,11-dien-3-one 
• 77333-06-3 Propionic acid (1S,2R,3S,6S)-3-isopropenyl-6-methyl-2-vinyl-cyclohexyl ester 
• 77333-05-2 Acetic acid (1S,2R,3S,6S)-3-isopropenyl-6-methyl-2-vinyl-cyclohexyl ester 
• 77333-12-1 (1S,2R,3S,6S)-3-Isopropenyl-6-methyl-2-vinyl-cyclohexanol 

Relevant articles and documents

Synthesis of (+)-sorokinianin

Sorokinianin (1), an inhibitor of barley germination, was synthesized in optically active form employing d-carvone as the only chiral source. The key steps are stereoselective intra- and intermolecular aldol reactions to construct the bicyclo[3.2.1]octane

Diels-Alder route to norbornane derived vicinal phosphane/borane frustrated Lewis pairs for the metal-free catalytic hydrogenation of α, β-unsaturated ketones

The [4+2] cycloaddition reaction of the (dimesitylphosphino)cyclopentadienes 5a,b with N-phenylmaleimide gave the norbornene derivative 9. Its reduction with LiAlH4 produced the N-phenylpyrrolidino-annulated system 10. Treatment with Piers' bor

Platinum Nanoparticles Stabilized by Glycerodendrimers: Synthesis and Application to the Hydrogenation of α,β-Unsaturated Ketones under Mild Conditions

Air-stable platinum nanoparticles stabilized by glycerodendrimers were prepared in water and analyzed by TEM. These platinum nanoparticles showed good catalytic activity for the reduction of α,β-unsaturated ketones to saturated ketones at room temperature in water or in water/THF (1:1) under H2 (101.3 kPa). The catalytic species was recovered and recycled several times.

Pichia stipitis OYE 2.6 variants with improved catalytic efficiencies from site-saturation mutagenesis libraries

An earlier directed evolution project using alkene reductase OYE 2.6 from Pichia stipitis yielded 13 active site variants with improved properties toward three homologous Baylis-Hillman adducts. Here, we probed the generality of these improvements by testing the wild-type and all 13 variants against a panel of 16 structurally-diverse electron-deficient alkenes. Several substrates were sterically demanding, and as hoped, creating additional active site volume yielded better conversions for these alkenes. The most impressive improvement was found for 2-butylidenecyclohexanone. The wild-type provided less than 20% conversion after 24 h; a triple mutant afforded more than 60% conversion in the same time period. Moreover, even wild-type OYE 2.6 can reduce cyclohexenones with very bulky 4-substituents efficiently.