(E)-N-cyclopropyl-3-(4-iodo-1,5-diphenyl-1H-pyrazol-3-yl)prop-2-enamide

Base Information

Chemical Name:(E)-N-cyclopropyl-3-(4-iodo-1,5-diphenyl-1H-pyrazol-3-yl)prop-2-enamide
CAS No.:1214997-55-3
Molecular Formula:C₂₁H₁₈IN₃O
Molecular Weight:455.298
Hs Code.:

Synonyms:(E)-N-cyclopropyl-3-(4-iodo-1,5-diphenyl-1H-pyrazol-3-yl)prop-2-enamide

Suppliers and Price of (E)-N-cyclopropyl-3-(4-iodo-1,5-diphenyl-1H-pyrazol-3-yl)prop-2-enamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-N-cyclopropyl-3-(4-iodo-1,5-diphenyl-1H-pyrazol-3-yl)prop-2-enamide

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Technology Process of (E)-N-cyclopropyl-3-(4-iodo-1,5-diphenyl-1H-pyrazol-3-yl)prop-2-enamide

There total 1 articles about (E)-N-cyclopropyl-3-(4-iodo-1,5-diphenyl-1H-pyrazol-3-yl)prop-2-enamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1214997-54-2
(E)-3-(4-iodo-1,5-diphenyl-1H-pyrazol-3-yl)prop-2-enoic acid

: 765-30-0
Cyclopropylamine

: 1214997-55-3
(E)-N-cyclopropyl-3-(4-iodo-1,5-diphenyl-1H-pyrazol-3-yl)prop-2-enamide

Guidance literature:: (E)-3-(4-iodo-1,5-diphenyl-1H-pyrazol-3-yl)prop-2-enoic acid; With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

Cyclopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 2h;
DOI:10.1002/adsc.200900438

Reference yield: 75.0%

: 1214997-55-3
(E)-N-cyclopropyl-3-(4-iodo-1,5-diphenyl-1H-pyrazol-3-yl)prop-2-enamide

: 1214997-57-5
N-cyclopropyl-3-(1,5-diphenyl-1H-pyrazol-3-yl)propanamide

Guidance literature:: With hydrogen; nickel; In methanol; at 20 ℃; for 3h; under 2068.65 Torr;
DOI:10.1002/adsc.200900438

Reference yield: 68.0%

: 1214997-55-3
(E)-N-cyclopropyl-3-(4-iodo-1,5-diphenyl-1H-pyrazol-3-yl)prop-2-enamide

: 1214997-56-4
(E)-N-cyclopropyl-3-(1,5-diphenyl-1H-pyrazol-3-yl)prop-2-enamide

Guidance literature:: With copper(l) iodide; caesium carbonate; ethylenediamine; In N,N-dimethyl-formamide; at 100 ℃; for 24h; Inert atmosphere;
DOI:10.1002/adsc.200900438