Donepezilbenzyl bromide

Base Information

Chemical Name:Donepezilbenzyl bromide
CAS No.:844694-85-5
Molecular Formula:Br*C₃₁H₃₆NO₃
Molecular Weight:550.536
Hs Code.:
UNII:2L83S3XLZA
Wikidata:Q27254890
Mol file:844694-85-5.mol

Synonyms:844694-85-5;Donepezilbenzyl bromide;Donepezil Benzyl Bromide (Donepezil Impurity);Donepezil benzyl bromide;(+/-)-Donepezilbenzyl bromide;2L83S3XLZA;Donepezil Benzyl Bromide Impurity;2-[(1,1-dibenzylpiperidin-1-ium-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;bromide;Piperidinium, 4-((2,3-dihydro-5,6-dimethoxy-1-oxo-1H-inden-2-yl)methyl)-1,1-bis(phenylmethyl)-, bromide (1:1);1,1-Dibenzyl-4-((5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)piperidin-1-ium bromide;UNII-2L83S3XLZA;1,1-Dibenzyl-4-[(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl]-1-piperidinium Bromide;2-[(1,1-Dibenzylpiperidin-1-ium-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one,bromide;Donepezil impurity, donepezilbenzyl bromide- [USP];AMY38946;Donepezil hydrochloride impurity, donepezilbenzyl bromide- [USP];MFCD16294188;AKOS030255252;SY248492;CS-0456146;FT-0667768;A1-06474;Q27254890;DONEPEZIL IMPURITY, DONEPEZILBENZYL BROMIDE- [USP IMPURITY];1,1-Dibenzyl-4-[(5,6-dimethoxy-1oxo-2,3-dihydro-1H-inden-2-yl)methyl]piperidinium Bromide;DONEPEZIL HYDROCHLORIDE IMPURITY, DONEPEZILBENZYL BROMIDE- [USP IMPURITY];1,1-Dibenzyl-4-((5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)piperidin-1-iumbromide;1,1-dibenzyl-4-((5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)piperidinium bromide;4-[(2,3-Dihydro-5,6-dimethoxy-1-oxo-1H-inden-2-yl)methyl]-1,1-bis(phenylmethyl) Piperidinium Bromide

Suppliers and Price of Donepezilbenzyl bromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
DonepezilBenzylBromide(DonepezilImpurity)
10mg
$ 310.00

Medical Isotopes, Inc.
DonepezilBenzylBromide(DonepezilImpurity) 98%minimum
0 Null
$ 3900.00

Biosynth Carbosynth
Donepezil benzyl bromide (donepezil impurity)
25 mg
$ 300.00

Biosynth Carbosynth
Donepezil benzyl bromide (donepezil impurity)
10 mg
$ 150.00

Biosynth Carbosynth
Donepezil benzyl bromide (donepezil impurity)
5 mg
$ 100.00

Biosynth Carbosynth
Donepezil benzyl bromide (donepezil impurity)
2 mg
$ 50.00

Biosynth Carbosynth
Donepezil benzyl bromide (donepezil impurity)
50 mg
$ 460.00

American Custom Chemicals Corporation
DONEPEZIL BENZYL BROMIDE 95.00%
5MG
$ 330.00

AK Scientific
Donepezilbenzylbromide
1g
$ 2085.00

A1 Biochem Labs
DonepezilBenzylBromideImpurity 95%
200 mg
$ 1350.00

Total 12 raw suppliers

Chemical Property of Donepezilbenzyl bromide

Chemical Property:

Melting Point:191-196°C
PSA：35.53000
LogP:3.03890
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly, Heated), Methanol (Slightly, Heated)
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:549.18786
Heavy Atom Count:36
Complexity:653

Purity/Quality:

99% ^*data from raw suppliers

DonepezilBenzylBromide(DonepezilImpurity) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C2C(=C1)CC(C2=O)CC3CC[N+](CC3)(CC4=CC=CC=C4)CC5=CC=CC=C5)OC.[Br-]

Technology Process of Donepezilbenzyl bromide

There total 7 articles about Donepezilbenzyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 100-39-0
benzyl bromide

: 142057-77-0
donepezil hydrochloride

: 844694-85-5
1,1-dibenzyl-4-(5,6-dimethoxy-1-oxo-indan-2-ylmethyl)-piperidinium; bromide

Guidance literature:: 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride; With sodium hydroxide; In dichloromethane; water monomer;

benzyl bromide; In dichloromethane; water monomer; Reflux;