N-methyl-4-methyl-α-bromoacetanilide

Base Information

• Chemical Name: N-methyl-4-methyl-α-bromoacetanilide
• CAS No.: 1319751-61-5
• Molecular Formula: C₁₀H₁₂BrNO
• Molecular Weight: 242.115
• Mol file: 1319751-61-5.mol

Synonyms:N-methyl-4-methyl-α-bromoacetanilide

Chemical Property of N-methyl-4-methyl-α-bromoacetanilide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-methyl-4-methyl-α-bromoacetanilide

There total 3 articles about N-methyl-4-methyl-α-bromoacetanilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-methyl-p-toluidine (623-08-5) + 2-Bromoacetyl bromide (598-21-0) → N-methyl-4-methyl-α-bromoacetanilide (1319751-61-5)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1h;

DOI:10.1039/c8cc02472c

Reference yield:

4-(N-methylacetamido)toluene (612-03-3) → N-methyl-4-methyl-α-bromoacetanilide (1319751-61-5)

Guidance literature:

With copper(ll) bromide; In ethyl acetate; at 20 ℃;

DOI:10.1002/adsc.202101053

Reference yield:

bromoacetic anhydride (13094-51-4) + N-methyl-p-toluidine (623-08-5) → N-methyl-4-methyl-α-bromoacetanilide (1319751-61-5)

Guidance literature:

In diethyl ether;

DOI:10.5012/bkcs.2011.32.3.857

upstream raw materials:

bromoacetic anhydride

N-methyl-p-toluidine

2-Bromoacetyl bromide

4-(N-methylacetamido)toluene

Downstream raw materials:

4-chloro-benzylamine; hydrobromide

(4-methoxyphenyl)methanaminium bromide

benzylamine hydrobromide

p-methylbenzylamine hydrobromide