N⁴-[2-(2,2,2-trifluoroacetamido)ethyl]-5'-O-(4-methoxytrityl)-2'-deoxycytidine

Base Information

Chemical Name:N⁴-[2-(2,2,2-trifluoroacetamido)ethyl]-5'-O-(4-methoxytrityl)-2'-deoxycytidine
CAS No.:745062-93-5
Molecular Formula:C₃₃H₃₃F₃N₄O₆
Molecular Weight:638.643
Hs Code.:

N<sup>4</sup>-[2-(2,2,2-trifluoroacetamido)ethyl]-5'-O-(4-methoxytrityl)-2'-deoxycytidine

Synonyms:N⁴-[2-(2,2,2-trifluoroacetamido)ethyl]-5'-O-(4-methoxytrityl)-2'-deoxycytidine

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Chemical Property of N⁴-[2-(2,2,2-trifluoroacetamido)ethyl]-5'-O-(4-methoxytrityl)-2'-deoxycytidine

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Technology Process of N⁴-[2-(2,2,2-trifluoroacetamido)ethyl]-5'-O-(4-methoxytrityl)-2'-deoxycytidine

There total 4 articles about N⁴-[2-(2,2,2-trifluoroacetamido)ethyl]-5'-O-(4-methoxytrityl)-2'-deoxycytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 383-63-1
ethyl trifluoroacetate,

: 745062-92-4
N⁴-(2-aminoethyl)-5'-O-(4-monomethoxytrityl)-2'-deoxycytidine

: 745062-93-5
N⁴-[2-(2,2,2-trifluoroacetamido)ethyl]-5'-O-(4-methoxytrityl)-2'-deoxycytidine

Guidance literature:: In ethanol; at 0 ℃; for 1h;
DOI:10.1039/b403652b

Reference yield:

: 189005-86-5
4-(p-nitrophenoxy)-1-(β-D-2-deoxyribofuranosyl)pyrimidin-2(1H)-one

: 745062-93-5
N⁴-[2-(2,2,2-trifluoroacetamido)ethyl]-5'-O-(4-methoxytrityl)-2'-deoxycytidine

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / cooling

2: 0.93 g / ethanol / 2 h

3: 97 percent / ethanol / 1 h / 0 °C

With pyridine; In ethanol;
DOI:10.1039/b403652b

Reference yield:

: 14470-28-1
mono-4-methoxytrityl chloride

: 745062-93-5
N⁴-[2-(2,2,2-trifluoroacetamido)ethyl]-5'-O-(4-methoxytrityl)-2'-deoxycytidine

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / cooling

2: 0.93 g / ethanol / 2 h

3: 97 percent / ethanol / 1 h / 0 °C

With pyridine; In ethanol;
DOI:10.1039/b403652b