benzyl 4-(tertbutoxycarbonylamino)-2-(4-(triisopropylsilyloxy)phenyl)butanoate

Base Information

Chemical Name:benzyl 4-(tertbutoxycarbonylamino)-2-(4-(triisopropylsilyloxy)phenyl)butanoate
CAS No.:1253955-46-2
Molecular Formula:C₃₁H₄₇NO₅Si
Molecular Weight:541.803
Hs Code.:

Synonyms:benzyl 4-(tertbutoxycarbonylamino)-2-(4-(triisopropylsilyloxy)phenyl)butanoate

Suppliers and Price of benzyl 4-(tertbutoxycarbonylamino)-2-(4-(triisopropylsilyloxy)phenyl)butanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of benzyl 4-(tertbutoxycarbonylamino)-2-(4-(triisopropylsilyloxy)phenyl)butanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of benzyl 4-(tertbutoxycarbonylamino)-2-(4-(triisopropylsilyloxy)phenyl)butanoate

There total 4 articles about benzyl 4-(tertbutoxycarbonylamino)-2-(4-(triisopropylsilyloxy)phenyl)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1253955-45-1
benzyl 3-cyano-2-((triisopropylsilyloxy)phenyl)propanoate

: 1253955-46-2
benzyl 4-(tertbutoxycarbonylamino)-2-(4-(triisopropylsilyloxy)phenyl)butanoate

Guidance literature:: benzyl 3-cyano-2-((triisopropylsilyloxy)phenyl)propanoate; With methanol; sodium tetrahydroborate; cobalt(II) chloride hexahydrate; at 0 ℃; for 0.333333h;

With hydrogenchloride; In methanol; at 0 ℃; for 0.333333h;

di-tert-butyl dicarbonate; With triethylamine; In dichloromethane; at 0 ℃; for 1.5h;

Reference yield:

: 100-39-0
benzyl bromide

: 1253955-46-2
benzyl 4-(tertbutoxycarbonylamino)-2-(4-(triisopropylsilyloxy)phenyl)butanoate

Guidance literature:: Multi-step reaction with 4 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 0 °C

1.2: 0 - 20 °C

2.1: 2,6-dimethylpyridine / dichloromethane / 2.5 h / 0 °C

3.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 °C

3.2: 2 h / -78 - 0 °C

4.1: cobalt(II) chloride hexahydrate; sodium tetrahydroborate / methanol / 0.33 h / 0 °C

4.2: 0.33 h / 0 °C

4.3: 1.5 h / 0 °C

With 2,6-dimethylpyridine; sodium tetrahydroborate; cobalt(II) chloride hexahydrate; potassium carbonate; lithium hexamethyldisilazane; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 1253955-44-0
benzyl 2-(4-(triisopropylsiloxy)phenyl)acetate

: 1253955-46-2
benzyl 4-(tertbutoxycarbonylamino)-2-(4-(triisopropylsilyloxy)phenyl)butanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 °C

1.2: 2 h / -78 - 0 °C

2.1: cobalt(II) chloride hexahydrate; sodium tetrahydroborate / methanol / 0.33 h / 0 °C

2.2: 0.33 h / 0 °C

2.3: 1.5 h / 0 °C

With sodium tetrahydroborate; cobalt(II) chloride hexahydrate; lithium hexamethyldisilazane; In tetrahydrofuran; methanol;