2,3-bis(3-phenyl-1,2,4-oxadiazol-5-yl)-2-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)propanenitrile

Base Information

• Chemical Name: 2,3-bis(3-phenyl-1,2,4-oxadiazol-5-yl)-2-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)propanenitrile
• CAS No.: 7435-30-5
• Molecular Formula: C₂₈H₁₉N₇O₃
• Molecular Weight: 501.504
• Mol file: 7435-30-5.mol

Synonyms:2,3-bis(3-phenyl-1,2,4-oxadiazol-5-yl)-2-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)propanenitrile

Chemical Property of 2,3-bis(3-phenyl-1,2,4-oxadiazol-5-yl)-2-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)propanenitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-bis(3-phenyl-1,2,4-oxadiazol-5-yl)-2-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)propanenitrile

There total 3 articles about 2,3-bis(3-phenyl-1,2,4-oxadiazol-5-yl)-2-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)propanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

potassium cyanide + 5-(chloromethyl)-3-phenyl-1,2,4-oxadiazole (1822-94-2) → 5,5',5''-(propane-1,2,3-triyl)tris(3-phenyl-1,2,4-oxadiazole) + 2,3-bis(3-phenyl-1,2,4-oxadiazol-5-yl)-2-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)propanenitrile (7435-30-5)

Guidance literature:

In acetonitrile; at 20 ℃; for 24h; Time;

DOI:10.3762/bjoc.14.280

Reference yield:

N-hydroxybenzenecarboximidamide (613-92-3) → 2,3-bis(3-phenyl-1,2,4-oxadiazol-5-yl)-2-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)propanenitrile (7435-30-5)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene / Heating

2: dimethylsulfoxide

In dimethyl sulfoxide; toluene;

Reference yield:

sodium cyanide (143-33-9,25596-52-5) + 5-(chloromethyl)-3-phenyl-1,2,4-oxadiazole (1822-94-2) → 2,3-bis(3-phenyl-1,2,4-oxadiazol-5-yl)-2-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)propanenitrile (7435-30-5)

Guidance literature:

In dimethyl sulfoxide;

upstream raw materials:

sodium cyanide

5-(chloromethyl)-3-phenyl-1,2,4-oxadiazole

N-hydroxybenzenecarboximidamide