(R)-2-methyl-1-(2-methoxyphenyl)-1-propanol

Base Information

Chemical Name:(R)-2-methyl-1-(2-methoxyphenyl)-1-propanol
CAS No.:827348-36-7
Molecular Formula:C₁₁H₁₆O₂
Molecular Weight:180.247
Hs Code.:

Synonyms:(R)-2-methyl-1-(2-methoxyphenyl)-1-propanol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2-methyl-1-(2-methoxyphenyl)-1-propanol

Chemical Property:

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Technology Process of (R)-2-methyl-1-(2-methoxyphenyl)-1-propanol

There total 3 articles about (R)-2-methyl-1-(2-methoxyphenyl)-1-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 625-81-0
diisopropyl zinc

: 135-02-4
ortho-anisaldehyde

: 827348-36-7
(R)-2-methyl-1-(2-methoxyphenyl)-1-propanol

: (S)-2-methyl-1-(2-methoxyphenyl)-1-propanol

: 612-16-8
(2-methoxyphenyl)methanol

Guidance literature:: With C₃₅H₄₇N₅O₄; In toluene; at 0 - 20 ℃; for 12h; enantioselective reaction; Inert atmosphere;
DOI:10.1039/d0ra04554c

Reference yield:

: 74786-53-1
1-(2-methoxyphenyl)-2-methylpropan-1-one

: 827348-36-7
(R)-2-methyl-1-(2-methoxyphenyl)-1-propanol

: (S)-2-methyl-1-(2-methoxyphenyl)-1-propanol

Guidance literature:: With C₃₃H₂₉FeMnN₂O₃P⁽¹⁺⁾*Br^(1-); potassium tert-butylate; hydrogen; In ethanol; at 50 ℃; for 16h; under 37503.8 Torr; Overall yield = 91 %; enantioselective reaction; Autoclave;
DOI:10.1002/anie.201702406

Reference yield:

: 625-81-0
diisopropyl zinc

: 135-02-4
ortho-anisaldehyde

: 827348-36-7
(R)-2-methyl-1-(2-methoxyphenyl)-1-propanol

: (S)-2-methyl-1-(2-methoxyphenyl)-1-propanol

Guidance literature:: With (1R,2S)-ephedrine-end-functionalized polystyrene; In toluene; at 0 ℃; for 48h; Title compound not separated from byproducts.;
DOI:10.1016/j.tetasy.2007.12.020