Technology Process of 2-cyanoethyl [(5-phenyl-1 ,3,4-thiadiazol-2-yl)methyl]dithiocarbamate
There total 5 articles about 2-cyanoethyl [(5-phenyl-1 ,3,4-thiadiazol-2-yl)methyl]dithiocarbamate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
carbon disulfide; C-(5-Phenyl-[1,3,4]thiadiazol-2-yl)-methylamine;
With
triethylamine;
In
water;
for 0.0833333h;
bromopropionitrile;
In
water;
at 20 ℃;
for 2h;
DOI:10.1016/j.ejmech.2016.02.015
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: ethyl acetate / 3 h / Reflux
2.1: Lawessons reagent / toluene / 4 h / 115 °C / Inert atmosphere
3.1: sodium azide / N,N-dimethyl-formamide / 6 h / 20 °C / Inert atmosphere
4.1: hydrogen; palladium on activated charcoal / methanol / 20 °C / 3040.2 Torr
5.1: triethylamine / water / 0.08 h
5.2: 2 h / 20 °C
With
Lawessons reagent; sodium azide; palladium on activated charcoal; hydrogen; triethylamine;
In
methanol; water; ethyl acetate; N,N-dimethyl-formamide; toluene;
DOI:10.1016/j.ejmech.2016.02.015
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrogen; palladium on activated charcoal / methanol / 20 °C / 3040.2 Torr
2.1: triethylamine / water / 0.08 h
2.2: 2 h / 20 °C
With
palladium on activated charcoal; hydrogen; triethylamine;
In
methanol; water;
DOI:10.1016/j.ejmech.2016.02.015
