N-{[3-cyclohexyl-2-(4-fluorophenyl)-1-methyl-1H-imidazo[1,2-b]pyrazole-6-yl]carbonyl}-L-tryptophan

Base Information

Chemical Name:N-{[3-cyclohexyl-2-(4-fluorophenyl)-1-methyl-1H-imidazo[1,2-b]pyrazole-6-yl]carbonyl}-L-tryptophan
CAS No.:1427549-76-5
Molecular Formula:C₃₀H₃₀FN₅O₃
Molecular Weight:527.598
Hs Code.:

Synonyms:N-{[3-cyclohexyl-2-(4-fluorophenyl)-1-methyl-1H-imidazo[1,2-b]pyrazole-6-yl]carbonyl}-L-tryptophan

Suppliers and Price of N-{[3-cyclohexyl-2-(4-fluorophenyl)-1-methyl-1H-imidazo[1,2-b]pyrazole-6-yl]carbonyl}-L-tryptophan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-{[3-cyclohexyl-2-(4-fluorophenyl)-1-methyl-1H-imidazo[1,2-b]pyrazole-6-yl]carbonyl}-L-tryptophan

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-{[3-cyclohexyl-2-(4-fluorophenyl)-1-methyl-1H-imidazo[1,2-b]pyrazole-6-yl]carbonyl}-L-tryptophan

There total 9 articles about N-{[3-cyclohexyl-2-(4-fluorophenyl)-1-methyl-1H-imidazo[1,2-b]pyrazole-6-yl]carbonyl}-L-tryptophan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1427549-75-4
N-{[3-cyclohexyl-2-(4-fluorophenyl)-1-methyl-1H-imidazo[1,2-b]pyrazol-6-yl]carbonyl}-L-tryptophanate

: 1427549-76-5
N-{[3-cyclohexyl-2-(4-fluorophenyl)-1-methyl-1H-imidazo[1,2-b]pyrazole-6-yl]carbonyl}-L-tryptophan

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; methanol; at 60 ℃; for 2h;

Reference yield:

: 1427549-87-8
methyl 3-cyclohexyl-2-(4-fluorophenyl)-1-methyl-imidazo[1,2-b]pyrazole-6-carboxylate

: 1427549-76-5
N-{[3-cyclohexyl-2-(4-fluorophenyl)-1-methyl-1H-imidazo[1,2-b]pyrazole-6-yl]carbonyl}-L-tryptophan

Guidance literature:: Multi-step reaction with 3 steps

1: water; lithium hydroxide / tetrahydrofuran; methanol / 2 h / 60 °C

2: N-ethyl-N,N-diisopropylamine; HATU / dichloromethane / 2 h

3: water; lithium hydroxide / tetrahydrofuran; methanol / 2 h / 60 °C

With water; N-ethyl-N,N-diisopropylamine; HATU; lithium hydroxide; In tetrahydrofuran; methanol; dichloromethane;

Reference yield:

: 1427549-89-0
3-cyclohexyl-2-(4-fluorophenyl)-1-methyl-1H-imidazo[1,2-b]pyrazole-6-carboxylic acid

: 1427549-76-5
N-{[3-cyclohexyl-2-(4-fluorophenyl)-1-methyl-1H-imidazo[1,2-b]pyrazole-6-yl]carbonyl}-L-tryptophan

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine; HATU / dichloromethane / 2 h

2: water; lithium hydroxide / tetrahydrofuran; methanol / 2 h / 60 °C

With water; N-ethyl-N,N-diisopropylamine; HATU; lithium hydroxide; In tetrahydrofuran; methanol; dichloromethane;