(4aR,6R,7R,8R,8aS)-8-(4-Methoxy-benzyloxy)-2-phenyl-6-(2-tetradecyl-hexadecyloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol

Base Information

• Chemical Name: (4aR,6R,7R,8R,8aS)-8-(4-Methoxy-benzyloxy)-2-phenyl-6-(2-tetradecyl-hexadecyloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol
• CAS No.: 208661-97-6
• Molecular Formula: C₅₁H₈₄O₇
• Molecular Weight: 809.224
• Mol file: 208661-97-6.mol

Synonyms:(4aR,6R,7R,8R,8aS)-8-(4-Methoxy-benzyloxy)-2-phenyl-6-(2-tetradecyl-hexadecyloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol

Chemical Property of (4aR,6R,7R,8R,8aS)-8-(4-Methoxy-benzyloxy)-2-phenyl-6-(2-tetradecyl-hexadecyloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4aR,6R,7R,8R,8aS)-8-(4-Methoxy-benzyloxy)-2-phenyl-6-(2-tetradecyl-hexadecyloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol

There total 3 articles about (4aR,6R,7R,8R,8aS)-8-(4-Methoxy-benzyloxy)-2-phenyl-6-(2-tetradecyl-hexadecyloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzaldehyde dimethyl acetal (1125-88-8) → (4aR,6R,7R,8R,8aS)-8-(4-Methoxy-benzyloxy)-2-phenyl-6-(2-tetradecyl-hexadecyloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol (208661-97-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / H₂SO₄ / tetrahydrofuran / 20 h / Ambient temperature

2: 1.) Bu₂SnO, 2.) tetra n-butyl ammonium iodide / 1) toluene, reflux, 24 h; 2) THF, reflux, 24 h

With sulfuric acid; tetra-(n-butyl)ammonium iodide; di(n-butyl)tin oxide; In tetrahydrofuran;

DOI:10.1080/07328309808002905

Reference yield:

2-(tetradecyl)hexadecyl β-D-galactopyranoside (171733-54-3) → (4aR,6R,7R,8R,8aS)-8-(4-Methoxy-benzyloxy)-2-phenyl-6-(2-tetradecyl-hexadecyloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol (208661-97-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / H₂SO₄ / tetrahydrofuran / 20 h / Ambient temperature

2: 1.) Bu₂SnO, 2.) tetra n-butyl ammonium iodide / 1) toluene, reflux, 24 h; 2) THF, reflux, 24 h

With sulfuric acid; tetra-(n-butyl)ammonium iodide; di(n-butyl)tin oxide; In tetrahydrofuran;

DOI:10.1080/07328309808002905

Reference yield:

p-methoxybenzyl chloride (824-94-2) + (4aR,6R,7R,8R,8aR)-2-Phenyl-6-(2-tetradecyl-hexadecyloxy)-hexahydro-pyrano[3,2-d][1,3]dioxine-7,8-diol (196204-50-9) → (4aR,6R,7R,8R,8aS)-8-(4-Methoxy-benzyloxy)-2-phenyl-6-(2-tetradecyl-hexadecyloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol (208661-97-6)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; di(n-butyl)tin oxide; Yield given. Multistep reaction; 1) toluene, reflux, 24 h; 2) THF, reflux, 24 h;

DOI:10.1080/07328309808002905

upstream raw materials:

p-methoxybenzyl chloride

(4aR,6R,7R,8R,8aR)-2-Phenyl-6-(2-tetradecyl-hexadecyloxy)-hexahydro-pyrano[3,2-d][1,3]dioxine-7,8-diol

benzaldehyde dimethyl acetal

2-(tetradecyl)hexadecyl β-D-galactopyranoside

Downstream raw materials:

(4aR,6R,7R,8S,8aS)-8-(4-Methoxy-benzyloxy)-2-phenyl-6-(2-tetradecyl-hexadecyloxy)-7-((2S,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-hexahydro-pyrano[3,2-d][1,3]dioxine

(4aR,6R,7R,8S,8aS)-7-[(2S,3S,4R,5R,6S)-3,5-Bis-benzyloxy-4-(4-methoxy-benzyloxy)-6-methyl-tetrahydro-pyran-2-yloxy]-8-(4-methoxy-benzyloxy)-2-phenyl-6-(2-tetradecyl-hexadecyloxy)-hexahydro-pyrano[3,2-d][1,3]dioxine

(4aR,6R,7R,8S,8aR)-7-((2S,3S,4R,5S,6S)-3,5-Bis-benzyloxy-4-hydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-2-phenyl-6-(2-tetradecyl-hexadecyloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-8-ol

(4aR,6R,7R,8S,8aR)-2-Phenyl-6-(2-tetradecyl-hexadecyloxy)-7-((2S,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-8-ol