196204-50-9Relevant academic research and scientific papers
Synthesis of 2-O-Fucosyl Sulfatide, a Blocker of L- and P-Selectin
Ishida, Hideharu,Sago, Satoshi,Ikami, Takao,Kiso, Makoto,Hasegawa, Akira
, p. 1615 - 1616 (1997)
A new derivative of sulfatide, 2-O-α-L-fucopyranosyl sulfatide, was synthesized. The compound inhibited the binding of HL-60 cells, which express sialyl Lewis X, to P- and L-selectin more than the corresponding non fucosylated compound.
Synthetic studies on selectin ligands/inhibitors: Synthesis and inhibitory activity of 2-O-fucosyl sulfatides containing 2-branched fatty alkyl residues in place of ceramide
Ikami, Takao,Kakigami, Takuji,Baba, Kunihisa,Hamajima, Hitoshi,Jomori, Takahito,Usui, Toshinao,Suzuki, Yasuo,Tanaka, Harunari,Ishida, Hideharu,Hasegawa, Akira,Kiso, Makoto
, p. 453 - 470 (2007/10/03)
To investigate the biological selectin-ligand interactions, four sulfated 2-O-α-L-fucopyranosyl β-D-galactopyranosides containing 2-branched fatty-alkyl residues in place of ceramide have been systematically synthesized. The target glycolipids were assaye
