16,18-bis(ethoxycarbonyl)-2,5,8,11,14-pentaoxa-17-thiabicyclo<13.3.0>octadeca-1(18),15-diene

Base Information

• Chemical Name: 16,18-bis(ethoxycarbonyl)-2,5,8,11,14-pentaoxa-17-thiabicyclo<13.3.0>octadeca-1(18),15-diene
• CAS No.: 122372-64-9
• Molecular Formula: C₁₈H₂₆O₉S
• Molecular Weight: 418.465
• Mol file: 122372-64-9.mol

Synonyms:16,18-bis(ethoxycarbonyl)-2,5,8,11,14-pentaoxa-17-thiabicyclo<13.3.0>octadeca-1(18),15-diene

Chemical Property of 16,18-bis(ethoxycarbonyl)-2,5,8,11,14-pentaoxa-17-thiabicyclo<13.3.0>octadeca-1(18),15-diene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 16,18-bis(ethoxycarbonyl)-2,5,8,11,14-pentaoxa-17-thiabicyclo<13.3.0>octadeca-1(18),15-diene

There total 4 articles about 16,18-bis(ethoxycarbonyl)-2,5,8,11,14-pentaoxa-17-thiabicyclo<13.3.0>octadeca-1(18),15-diene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

Tetraethylene glycol (112-60-7) + 3,4-dihydroxythiophene-2,5-dicarboxylic acid diethyl ester (1822-66-8) → 16,18-bis(ethoxycarbonyl)-2,5,8,11,14-pentaoxa-17-thiabicyclo<13.3.0>octadeca-1(18),15-diene (122372-64-9)

Guidance literature:

With tributylphosphine; diamide; In tetrahydrofuran; at 60 ℃; Darkness; Inert atmosphere;

DOI:10.1016/j.tetlet.2011.03.062

Reference yield: 78.0%

3,4-dihydroxythiophene-2,5-dicarboxylic acid diethyl ester (1822-66-8) + 1,11-diiodo-3,6-9-trioxaundecane (36839-56-2) → 16,18-bis(ethoxycarbonyl)-2,5,8,11,14-pentaoxa-17-thiabicyclo<13.3.0>octadeca-1(18),15-diene (122372-64-9)

Guidance literature:

3,4-dihydroxythiophene-2,5-dicarboxylic acid diethyl ester; With cesium fluoride; In N,N-dimethyl-formamide; at 20 ℃; for 1h; Inert atmosphere;

1,11-diiodo-3,6-9-trioxaundecane; In N,N-dimethyl-formamide; at 80 ℃; for 10h; Inert atmosphere;

DOI:10.1039/c005284c

Reference yield: 2.0%

tetraethylene glycol di(p-toluenesulfonate) (37860-51-8) + 3,4-dihydroxythiophene-2,5-dicarboxylic acid diethyl ester (1822-66-8) → 16,18-bis(ethoxycarbonyl)-2,5,8,11,14-pentaoxa-17-thiabicyclo<13.3.0>octadeca-1(18),15-diene (122372-64-9) + 16,18,34,36-tetrakis(ethoxycarbonyl)-2,5,8,11,14,20,23,26,29,32-decaoxa-17,35-dithiatricyclo<31.3.0.015,19>hexatriaconta-1(36),15,18,33-tetraene

Guidance literature:

With cesium fluoride; In acetonitrile; for 20h; Heating;

DOI:10.1246/bcsj.62.838

upstream raw materials:

tetraethylene glycol di(p-toluenesulfonate)

3,4-dihydroxythiophene-2,5-dicarboxylic acid diethyl ester

Tetraethylene glycol

1,11-diiodo-3,6-9-trioxaundecane