[1-(4-chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-acetic acid 4-[2-(diethoxy-phosphoryloxy)-ethyl]-phenyl ester

Base Information

Chemical Name:[1-(4-chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-acetic acid 4-[2-(diethoxy-phosphoryloxy)-ethyl]-phenyl ester
CAS No.:1428774-23-5
Molecular Formula:C₃₁H₃₃ClNO₈P
Molecular Weight:614.032
Hs Code.:

Synonyms:[1-(4-chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-acetic acid 4-[2-(diethoxy-phosphoryloxy)-ethyl]-phenyl ester

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Chemical Property of [1-(4-chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-acetic acid 4-[2-(diethoxy-phosphoryloxy)-ethyl]-phenyl ester

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Technology Process of [1-(4-chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-acetic acid 4-[2-(diethoxy-phosphoryloxy)-ethyl]-phenyl ester

There total 1 articles about [1-(4-chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-acetic acid 4-[2-(diethoxy-phosphoryloxy)-ethyl]-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1355183-05-9
[1-(4-chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-acetic acid 4-(2-hydroxy-ethyl)-phenyl ester

: 814-49-3
diethyl chlorophosphate

: 1428774-23-5
[1-(4-chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-acetic acid 4-[2-(diethoxy-phosphoryloxy)-ethyl]-phenyl ester

Guidance literature:: With dmap; N-ethyl-N,N-diisopropylamine; In dichloromethane; Reflux;

Reference yield:

: 1428774-23-5
[1-(4-chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-acetic acid 4-[2-(diethoxy-phosphoryloxy)-ethyl]-phenyl ester

: C₁₂H₁₉O₅P

: 53-86-1
[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid

Guidance literature:: With glucose-6-phosphate dehydrogenase; β-D-glucose 6-phosphate; NADP; magnesium chloride; In aq. phosphate buffer; at 37 ℃; for 4h; pH=7.4; Time; Reagent/catalyst; Enzymatic reaction;
DOI:10.1016/j.bcp.2013.01.031

Reference yield:

: 1428774-23-5
[1-(4-chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-acetic acid 4-[2-(diethoxy-phosphoryloxy)-ethyl]-phenyl ester

: C₁₂H₁₉O₅P

: 1428774-26-8
C₃₁H₃₃ClNO₉P

: 1428774-24-6
C₃₀H₃₁ClNO₈P

: 53-86-1
[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid

Guidance literature:: With glucose-6-phosphate dehydrogenase; β-D-glucose 6-phosphate; NADP; magnesium chloride; In aq. phosphate buffer; at 37 ℃; pH=7.4; Time; Reagent/catalyst; Enzymatic reaction;
DOI:10.1016/j.bcp.2013.01.031