(R)-5-((R)-2-AMINO-2-CARBOXYETHYL)-4,5-DIHYDROISOXAZOLE-3-CARBOXYLIC ACID

Base Information

Chemical Name:(R)-5-((R)-2-AMINO-2-CARBOXYETHYL)-4,5-DIHYDROISOXAZOLE-3-CARBOXYLIC ACID
CAS No.:824394-11-8
Molecular Formula:C₇H₁₀N₂O₅
Molecular Weight:202.167
Hs Code.:
Mol file:824394-11-8.mol

Synonyms:(R)-5-((R)-2-AMINO-2-CARBOXYETHYL)-4,5-DIHYDROISOXAZOLE-3-CARBOXYLIC ACID

Suppliers and Price of (R)-5-((R)-2-AMINO-2-CARBOXYETHYL)-4,5-DIHYDROISOXAZOLE-3-CARBOXYLIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(R)-5-((R)-2-AMINO-2-CARBOXYETHYL)-4,5-DIHYDROISOXAZOLE-3-CARBOXYLIC ACID 95.00%
5MG
$ 495.26

Total 3 raw suppliers

Chemical Property of (R)-5-((R)-2-AMINO-2-CARBOXYETHYL)-4,5-DIHYDROISOXAZOLE-3-CARBOXYLIC ACID

Chemical Property:

PSA：122.21000
LogP:-0.84620

Purity/Quality:

95% ^*data from raw suppliers

(R)-5-((R)-2-AMINO-2-CARBOXYETHYL)-4,5-DIHYDROISOXAZOLE-3-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (R)-5-((R)-2-AMINO-2-CARBOXYETHYL)-4,5-DIHYDROISOXAZOLE-3-CARBOXYLIC ACID

There total 30 articles about (R)-5-((R)-2-AMINO-2-CARBOXYETHYL)-4,5-DIHYDROISOXAZOLE-3-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 156426-54-9
(2S,5'S)-2-(N-(benzyloxycarbonyl)amino)-3-(3-carboxy-2-isoxazolin-5-yl)propanoic acid

: 824394-11-8
(2S,5'S)-2-amino-3-(3-carboxy-2-isoxazolin-5-yl)propanoic acid

Guidance literature:: With chloro-trimethyl-silane; sodium iodide; In acetonitrile; at 20 ℃; for 1.5h;
DOI:10.1021/ja00094a004

Reference yield: 40.0%

: 156426-53-8
(2S,5'R)-2-(N-(benzyloxycarbonyl)amino)-3-(3-carboxy-2-isoxazolin-5-yl)propanoic acid

: 824394-11-8
(2S,5'R)-2-amino-3-(3-carboxy-2-isoxazolin-5-yl)propanoic acid

Guidance literature:: With chloro-trimethyl-silane; sodium iodide; In acetonitrile; at 20 ℃; for 1.5h;
DOI:10.1021/ja00094a004

Reference yield:

: 16338-48-0
L-allylglycine

: 824394-11-8
(2S,5'S)-2-amino-3-(3-carboxy-2-isoxazolin-5-yl)propanoic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 96 percent / HCl

2: 45 percent / Et₃N, 4-(N,N-dimethylamino)pyridine / CHCl₃ / 19 h / 20 °C

3: 39 percent / aq. Na₂CO₃ / diethyl ether / 4 h / 20 °C

4: 99 percent / 10percent aq. NaOH / 21 h

5: 93 percent / TMSCl, NaI / acetonitrile / 1.5 h / 20 °C

With hydrogenchloride; dmap; sodium hydroxide; chloro-trimethyl-silane; sodium carbonate; triethylamine; sodium iodide; In diethyl ether; chloroform; acetonitrile;
DOI:10.1021/ja00094a004