(R)-2-methyl-1-{2-[4'-(tetrahydro-pyran-4-sulfonyl)-biphenyl-4-yl]-ethyl}-pyrrolidine hydrochloride

Base Information

Chemical Name:(R)-2-methyl-1-{2-[4'-(tetrahydro-pyran-4-sulfonyl)-biphenyl-4-yl]-ethyl}-pyrrolidine hydrochloride
CAS No.:1021169-42-5
Molecular Formula:C₂₄H₃₁NO₃S*ClH
Molecular Weight:450.042
Hs Code.:

Synonyms:(R)-2-methyl-1-{2-[4'-(tetrahydro-pyran-4-sulfonyl)-biphenyl-4-yl]-ethyl}-pyrrolidine hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2-methyl-1-{2-[4'-(tetrahydro-pyran-4-sulfonyl)-biphenyl-4-yl]-ethyl}-pyrrolidine hydrochloride

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Technology Process of (R)-2-methyl-1-{2-[4'-(tetrahydro-pyran-4-sulfonyl)-biphenyl-4-yl]-ethyl}-pyrrolidine hydrochloride

There total 1 articles about (R)-2-methyl-1-{2-[4'-(tetrahydro-pyran-4-sulfonyl)-biphenyl-4-yl]-ethyl}-pyrrolidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: (R)-4-(2-(2-methylpyrrolidin-1-yl)ethyl)phenylboronic Acid

: 1021169-68-5
4-[(4-bromophenyl)sulfonyl]tetrahydro-2H-pyran

: 1021169-42-5
(R)-2-methyl-1-{2-[4'-(tetrahydro-pyran-4-sulfonyl)-biphenyl-4-yl]-ethyl}-pyrrolidine hydrochloride

Guidance literature:: (R)-4-(2-(2-methylpyrrolidin-1-yl)ethyl)phenylboronic Acid; 4-[(4-bromophenyl)sulfonyl]tetrahydro-2H-pyran; With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; water; benzene; at 100 ℃; for 1h; Microwave irradiation;

With hydrogenchloride; In methanol; diethyl ether; ethyl acetate;