1-(2,6-diisopropylphenyl)-4-(2,4,6-trimethylphenyl)-1H-1,2,3-triazole

Base Information

• Chemical Name: 1-(2,6-diisopropylphenyl)-4-(2,4,6-trimethylphenyl)-1H-1,2,3-triazole
• CAS No.: 1263862-49-2
• Molecular Formula: C₂₃H₂₉N₃
• Molecular Weight: 347.503
• Mol file: 1263862-49-2.mol

Synonyms:1-(2,6-diisopropylphenyl)-4-(2,4,6-trimethylphenyl)-1H-1,2,3-triazole

Chemical Property of 1-(2,6-diisopropylphenyl)-4-(2,4,6-trimethylphenyl)-1H-1,2,3-triazole

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 1-(2,6-diisopropylphenyl)-4-(2,4,6-trimethylphenyl)-1H-1,2,3-triazole

There total 1 articles about 1-(2,6-diisopropylphenyl)-4-(2,4,6-trimethylphenyl)-1H-1,2,3-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2-ethynyl-1,3,5-trimethylbenzene (769-26-6) + 2,6-diisopropyl-1-azidobenzene (136551-45-6) → 1-(2,6-diisopropylphenyl)-4-(2,4,6-trimethylphenyl)-1H-1,2,3-triazole (1263862-49-2)

Guidance literature:

With CH₃(C₂N₃)Ph₂CuCl; at 100 ℃; for 5.5h;

DOI:10.1021/ol102858u

Reference yield: 81.0%

1-(2,6-diisopropylphenyl)-4-(2,4,6-trimethylphenyl)-1H-1,2,3-triazole (1263862-49-2) → 1-(2,6-diisopropylphenyl)-5-iodo-4-(2,4,6-trimethylphenyl)-1H-1,2,3-triazole

Guidance literature:

1-(2,6-diisopropylphenyl)-4-(2,4,6-trimethylphenyl)-1H-1,2,3-triazole; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.333333h; Schlenk technique; Inert atmosphere;

With iodine; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 16h; Schlenk technique; Inert atmosphere;

DOI:10.1039/C8CC05309J

Reference yield: 72.0%

1-(2,6-diisopropylphenyl)-4-(2,4,6-trimethylphenyl)-1H-1,2,3-triazole (1263862-49-2) + methyl iodide (74-88-4) → C24H32N3(1+)*I(1-) (1381990-63-1)

Guidance literature:

In acetonitrile; at 70 ℃; for 72h; Inert atmosphere; Schlenk technique;

DOI:10.1002/ejic.202100273

upstream raw materials:

2-ethynyl-1,3,5-trimethylbenzene

2,6-diisopropyl-1-azidobenzene

Downstream raw materials:

C₂₄H₃₂N₃⁽¹⁺⁾*I^(1-)