N-(3-{(R)-1-hydroxy-2-[3-(5-hydroxymethylindol-1-yl)-1,1-dimethylpropylamino]ethyl}phenyl)benzenesulphonamide hydrotrifluoroacetate

Base Information

Chemical Name:N-(3-{(R)-1-hydroxy-2-[3-(5-hydroxymethylindol-1-yl)-1,1-dimethylpropylamino]ethyl}phenyl)benzenesulphonamide hydrotrifluoroacetate
CAS No.:936003-91-7
Molecular Formula:C₂HF₃O₂*C₂₈H₃₃N₃O₄S
Molecular Weight:621.678
Hs Code.:

Synonyms:N-(3-{(R)-1-hydroxy-2-[3-(5-hydroxymethylindol-1-yl)-1,1-dimethylpropylamino]ethyl}phenyl)benzenesulphonamide hydrotrifluoroacetate

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Chemical Property of N-(3-{(R)-1-hydroxy-2-[3-(5-hydroxymethylindol-1-yl)-1,1-dimethylpropylamino]ethyl}phenyl)benzenesulphonamide hydrotrifluoroacetate

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Technology Process of N-(3-{(R)-1-hydroxy-2-[3-(5-hydroxymethylindol-1-yl)-1,1-dimethylpropylamino]ethyl}phenyl)benzenesulphonamide hydrotrifluoroacetate

There total 1 articles about N-(3-{(R)-1-hydroxy-2-[3-(5-hydroxymethylindol-1-yl)-1,1-dimethylpropylamino]ethyl}phenyl)benzenesulphonamide hydrotrifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 936004-18-1
N-benzenesulphonyl-N-(3-{(R)-2-[3-(5-formyl-indol-1-yl)-1,1-dimethyl-propylamino]-1-hydroxy-ethyl}-phenyl)-benzenesulphonamide

: 76-05-1
trifluoroacetic acid

: 936003-91-7
N-(3-{(R)-1-hydroxy-2-[3-(5-hydroxymethylindol-1-yl)-1,1-dimethylpropylamino]ethyl}phenyl)benzenesulphonamide hydrotrifluoroacetate

Guidance literature:: N-benzenesulphonyl-N-(3-{(R)-2-[3-(5-formyl-indol-1-yl)-1,1-dimethyl-propylamino]-1-hydroxy-ethyl}-phenyl)-benzenesulphonamide; With sodium tetrahydroborate; In methanol; at 20 ℃; for 1.16667h;

With sodium hydroxide; water; In methanol; N,N-dimethyl-formamide; at 20 ℃; for 2h;

trifluoroacetic acid;