Technology Process of C17H14ClFN4O2
There total 11 articles about C17H14ClFN4O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: thionyl chloride / N,N-dimethyl acetamide
2: potassium carbonate / water; dimethyl sulfoxide / 6 h / 70 - 75 °C
With
thionyl chloride; potassium carbonate;
In
N,N-dimethyl acetamide; water; dimethyl sulfoxide;
DOI:10.1021/op4002824
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium carbonate / water / 1 h / 40 - 45 °C / Large scale
1.2: 1 h / 10 - 25 °C / Large scale
2.1: sulfuric acid; nitric acid / 1 h / 0 - 15 °C / Large scale
3.1: methanol; sodium hydroxide / 1.67 h / 20 - 40 °C / Large scale
4.1: sodium hydroxide; palladium 10% on activated carbon; hydrogen / methanol / 3 h / 20 °C
5.1: thionyl chloride / N,N-dimethyl acetamide
6.1: potassium carbonate / water; dimethyl sulfoxide / 6 h / 70 - 75 °C
With
methanol; thionyl chloride; sulfuric acid; palladium 10% on activated carbon; hydrogen; nitric acid; sodium carbonate; potassium carbonate; sodium hydroxide;
In
methanol; N,N-dimethyl acetamide; water; dimethyl sulfoxide;
DOI:10.1021/op4002824
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium acetate; palladium 10% on activated carbon; hydrogen / methanol / 3 h / 20 °C
2: thionyl chloride / N,N-dimethyl acetamide
3: potassium carbonate / water; dimethyl sulfoxide / 6 h / 70 - 75 °C
With
thionyl chloride; palladium 10% on activated carbon; hydrogen; sodium acetate; potassium carbonate;
In
methanol; N,N-dimethyl acetamide; water; dimethyl sulfoxide;
DOI:10.1021/op4002824
