N₂-(2-aminoethyl)-N₅-(2-((3-azido-2,4,5-trifluoro-6-nitrophenyl)amino)ethyl)-3,6-bis(propylamino)pyrazine-2,5-dicarboxamide

Base Information

• Chemical Name: N₂-(2-aminoethyl)-N₅-(2-((3-azido-2,4,5-trifluoro-6-nitrophenyl)amino)ethyl)-3,6-bis(propylamino)pyrazine-2,5-dicarboxamide
• CAS No.: 1314607-39-0
• Molecular Formula: C₂₂H₂₉F₃N₁₂O₄
• Molecular Weight: 582.545

Synonyms:N₂-(2-aminoethyl)-N₅-(2-((3-azido-2,4,5-trifluoro-6-nitrophenyl)amino)ethyl)-3,6-bis(propylamino)pyrazine-2,5-dicarboxamide

Chemical Property of N₂-(2-aminoethyl)-N₅-(2-((3-azido-2,4,5-trifluoro-6-nitrophenyl)amino)ethyl)-3,6-bis(propylamino)pyrazine-2,5-dicarboxamide

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Technology Process of N₂-(2-aminoethyl)-N₅-(2-((3-azido-2,4,5-trifluoro-6-nitrophenyl)amino)ethyl)-3,6-bis(propylamino)pyrazine-2,5-dicarboxamide

There total 1 articles about N₂-(2-aminoethyl)-N₅-(2-((3-azido-2,4,5-trifluoro-6-nitrophenyl)amino)ethyl)-3,6-bis(propylamino)pyrazine-2,5-dicarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N2,N5-bis(2-aminoethyl)-3,6-bis(propylamino)pyrazine-2,5-dicarboxamide trifluoroacetate + 4-azido-1-nitro-2,3,5,6-tetrafluorobenzene (69173-92-8) → N2-(2-aminoethyl)-N5-(2-((3-azido-2,4,5-trifluoro-6-nitrophenyl)amino)ethyl)-3,6-bis(propylamino)pyrazine-2,5-dicarboxamide (1314607-39-0)

Guidance literature:

N₂,N₅-bis(2-aminoethyl)-3,6-bis(propylamino)pyrazine-2,5-dicarboxamide trifluoroacetate; With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 0 ℃; for 0.5h; Inert atmosphere;

4-azido-1-nitro-2,3,5,6-tetrafluorobenzene; In acetonitrile; at 20 ℃; for 1h; Inert atmosphere;

Reference yield:

N2-(2-aminoethyl)-N5-(2-((3-azido-2,4,5-trifluoro-6-nitrophenyl)amino)ethyl)-3,6-bis(propylamino)pyrazine-2,5-dicarboxamide (1314607-39-0) + folate (59-30-3) → N2-(2-aminoethyl)-N5-(2-((3-azido-2,4,5-trifluoro-6-nitrophenyl)amino)ethyl)-3,6-bis(propylamino)pyrazine-2,5-dicarboxamide

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In water; dimethyl sulfoxide; at 20 ℃; Inert atmosphere;

upstream raw materials:

4-azido-1-nitro-2,3,5,6-tetrafluorobenzene

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