Technology Process of (2R,3R)-isopropyl 3-(4-methoxyphenyl)glycidate
There total 8 articles about (2R,3R)-isopropyl 3-(4-methoxyphenyl)glycidate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
4-methylpyridine-1-oxide; sodium hypochlorite;
(salen)Mn(III)-complex;
In
water; benzene;
at 4 ℃;
for 24h;
Yield given;
DOI:10.1016/S0040-4020(01)89369-8
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 99 percent / Br2
2: 51 percent / KOH / aq. ethanol / 12 h / Heating
3: 81 percent / DCC, 4-dimethylaminopyridine / CH2Cl2 / 12 h / Ambient temperature
4: quinoline, H2 / Lindlar catalyst / hexane; various solvent(s) / 760 Torr / Ambient temperature
5: 55 percent / 1,2-dichloro-ethane / 24 h / Irradiation
6: 4-picoline-N-oxide, sodium hypochlorite / (salen)Mn(III)-complex / benzene; H2O / 24 h / 4 °C
With
4-methylpyridine-1-oxide; quinoline; dmap; potassium hydroxide; sodium hypochlorite; hydrogen; bromine; dicyclohexyl-carbodiimide;
Lindlar's catalyst;
In
ethanol; hexane; dichloromethane; water; 1,2-dichloro-ethane; benzene;
DOI:10.1016/S0040-4020(01)89369-8
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 51 percent / KOH / aq. ethanol / 12 h / Heating
2: 81 percent / DCC, 4-dimethylaminopyridine / CH2Cl2 / 12 h / Ambient temperature
3: quinoline, H2 / Lindlar catalyst / hexane; various solvent(s) / 760 Torr / Ambient temperature
4: 55 percent / 1,2-dichloro-ethane / 24 h / Irradiation
5: 4-picoline-N-oxide, sodium hypochlorite / (salen)Mn(III)-complex / benzene; H2O / 24 h / 4 °C
With
4-methylpyridine-1-oxide; quinoline; dmap; potassium hydroxide; sodium hypochlorite; hydrogen; dicyclohexyl-carbodiimide;
Lindlar's catalyst;
In
ethanol; hexane; dichloromethane; water; 1,2-dichloro-ethane; benzene;
DOI:10.1016/S0040-4020(01)89369-8
