24393-56-4Relevant articles and documents
Tuning and enhancement of the Mizoroki-Heck reaction using polarized Pd nanocomposite carbon aerogels
Martín, Laura,Molins, Elies,Vallribera, Adelina
, p. 10208 - 10212 (2016)
The application of a positive electric field on a Pd(0)-carbon aerogel nanocomposite enhances the reaction rate of the Mizoroki-Heck reaction. By contrast, when a negative potential is employed the reaction is inhibited. On the other hand, chronoamperometry measurements have revealed the polarizing current intensity as an indirect measure of the reaction evolution. The cationic nature of the reaction intermediates was unambiguously confirmed and a polar mechanism has been finally proposed.
Barium Hydroxide as Catalyst in Organic Reactions; V. Application in the Horner Reaction under Solid-Liquid Phase-Transfer Conditions
Sinisterra, J. V.,Mouloungui, Z.,Delmas, M.,Gaset, A.
, p. 1097 - 1100 (1985)
A new application of a barium hydroxide catalyst for the Horner reaction is described.The scope of the synthetic method is shown; furthermore, the yields are higher and the reaction times shorter than those previously reported for similar experimental conditions (solid-liquid).Ethyl 3-(1'-pyrenyl)-acrylate and the 3-(1'-pyrenyl)-acrylonitrile are described for the first time.
Asymmetric synthesis of piperidines using the nitro-Mannich reaction☆
Anderson, James C.,Bouvier-Israel, Eva,Rundell, Christopher D.,Zhang, Xiangyu
, (2020/12/21)
A method for the synthesis of functionalized piperidines containing 3 contiguous stereocentres in the 2-,3- and 4- positions uses a diastereoselective nitro-Mannich to control stereochemistry. The nitro-Mannich reaction between a β-aryl/heteroaryl substituted nitroalkanes and glyoxylate imine provides β-nitro-amines with good selectivity (70:30 to >95:5) for the syn, anti-diastereoisomers. Reductive cyclisation with BF3.OEt2 and Et3SiH gave, after purification, stereochemically pure piperidines in 19–57% yield for ten examples with different 4-aryl/heteroaryl substituents.
Pd/Cu-Free Cobalt-Catalyzed Suzuki and Heck Using Green Bio-Magnetic Hybrid and DFT-Based Theoretical Study
Hajipour, Abdol R.,Khorsandi, Zahra,Ahmadi, Mehnoosh,Jouypazadeh, Hamidreza,Mohammadi, Bahareh,Farrokhpour, Hossein
, p. 2842 - 2850 (2021/02/01)
Abstract: Several highly efficient and magnetically recyclable cobalt catalytic systems were prepared using magnetic chitosan and some safe and available organic compounds (Co-ligand@MNPs/Ch). The structure of these nanocomposites was confirmed by various physicochemical techniques such as FT-IR, XRD, TGA, VSM, TEM, SEM, CHNS and ICP-OES. These nano composites exhibit remarkable catalytic efficiency for Suzuki and Heck cross-coupling reactions in mild and green reaction conditions. The facile accessibility of starting materials, possible performance in air and eco-friendly conditions are merits of our catalysts. In addition, to describe and go insight to role and effect of ligands present in these catalysts, electrostatic interactions, density functional theory (DFT) model in molecular method were employed. Graphic Abstract: [Figure not available: see fulltext.]
