iodo-3,5-dimethyl-2-(prop-2-yn-1-yloxy)benzene

Base Information

• Chemical Name: iodo-3,5-dimethyl-2-(prop-2-yn-1-yloxy)benzene
• CAS No.: 1374746-75-4
• Molecular Formula: C₁₁H₁₁IO
• Molecular Weight: 286.112
• Mol file: 1374746-75-4.mol

Synonyms:iodo-3,5-dimethyl-2-(prop-2-yn-1-yloxy)benzene

Chemical Property of iodo-3,5-dimethyl-2-(prop-2-yn-1-yloxy)benzene

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of iodo-3,5-dimethyl-2-(prop-2-yn-1-yloxy)benzene

There total 1 articles about iodo-3,5-dimethyl-2-(prop-2-yn-1-yloxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1-iodo-3,5-dimethyl-4-hydroxybenzene (90003-93-3) + propargyl bromide (106-96-7) → iodo-3,5-dimethyl-2-(prop-2-yn-1-yloxy)benzene (1374746-75-4)

Guidance literature:

With potassium carbonate; In acetonitrile; at 50 ℃; for 48h;

DOI:10.1055/s-0036-1588655

Reference yield: 85.0%

iodo-3,5-dimethyl-2-(prop-2-yn-1-yloxy)benzene (1374746-75-4) + N-hydroxy-4-methylbenzenecarboximidoyl chloride (36288-37-6) → 5-[(2-iodo-4,6-dimethylphenoxy)methyl]-3-(p-tolyl)isoxazole

Guidance literature:

With copper(l) iodide; potassium carbonate; In diethyl ether; at 20 ℃; for 6h;

DOI:10.1055/s-0036-1588655

Reference yield:

iodo-3,5-dimethyl-2-(prop-2-yn-1-yloxy)benzene (1374746-75-4) + benzyl azide (622-79-7) → C18H18IN3O

Guidance literature:

With copper(l) iodide; N,N,N,N,-tetramethylethylenediamine; In N,N-dimethyl-formamide; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1002/ejoc.201101816

upstream raw materials:

1-iodo-3,5-dimethyl-4-hydroxybenzene

propargyl bromide

Downstream raw materials:

C₁₈H₁₇N₃O

C₁₇H₁₅N₃O