6-N-benzoyl-2'-O-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-secoadenosine

Base Information

Chemical Name:6-N-benzoyl-2'-O-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-secoadenosine
CAS No.:1120329-51-2
Molecular Formula:C₄₅H₄₁N₅O₈
Molecular Weight:779.849
Hs Code.:

Synonyms:6-N-benzoyl-2'-O-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-secoadenosine

Suppliers and Price of 6-N-benzoyl-2'-O-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-secoadenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of 6-N-benzoyl-2'-O-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-secoadenosine

Chemical Property:

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of 6-N-benzoyl-2'-O-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-secoadenosine

There total 5 articles about 6-N-benzoyl-2'-O-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-secoadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1044505-21-6
6-N-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-secoadenosine

: 98-88-4
benzoyl chloride

: 1120329-51-2
6-N-benzoyl-2'-O-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-secoadenosine

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at -78 ℃; for 1.25h; Inert atmosphere;
DOI:10.1016/j.bmc.2009.06.045

Reference yield:

: 4546-55-8
N-benzoyladenosine

: 1120329-51-2
6-N-benzoyl-2'-O-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-secoadenosine

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / 2 h / 25 °C

2: sodium periodate / 1,4-dioxane; water / 1 h / 25 °C

3: sodium tetrahydroborate; water / 1,4-dioxane / 1 h / 25 °C

4: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 1 h / -70 °C

With pyridine; sodium tetrahydroborate; sodium periodate; water; 1,8-diazabicyclo[5.4.0]undec-7-ene; In 1,4-dioxane; dichloromethane; water;

Reference yield:

: 129666-75-7,81246-82-4
6-N-benzoyl-5'-O-(4,4'-dimethoxytrityl)adenosine

: 1120329-51-2
6-N-benzoyl-2'-O-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-secoadenosine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium periodate / 1,4-dioxane; water / 1 h / 25 °C

2: sodium tetrahydroborate; water / 1,4-dioxane / 1 h / 25 °C

3: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 1 h / -70 °C

With sodium tetrahydroborate; sodium periodate; water; 1,8-diazabicyclo[5.4.0]undec-7-ene; In 1,4-dioxane; dichloromethane; water;