(Z)-2-[2-(TritylaMino)thiazol-4-yl]-2-(trityloxyiMino)acetic Acid Ethyl Ester

Base Information

Chemical Name:(Z)-2-[2-(TritylaMino)thiazol-4-yl]-2-(trityloxyiMino)acetic Acid Ethyl Ester
CAS No.:69689-86-7
Molecular Formula:C₄₅H₃₇N₃O₃S
Molecular Weight:699.873
Hs Code.:
Mol file:69689-86-7.mol

Synonyms:ethyl 2-(2-tritylaminothiazol-4-yl)-(Z)-2-(tritylhydroxyimino)acetate

Suppliers and Price of (Z)-2-[2-(TritylaMino)thiazol-4-yl]-2-(trityloxyiMino)acetic Acid Ethyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(Z)-2-[2-(Tritylamino)thiazol-4-yl]-2-(trityloxyimino)aceticAcidEthylEster
1g
$ 1075.00

TRC
(Z)-2-[2-(Tritylamino)thiazol-4-yl]-2-(trityloxyimino)aceticAcidEthylEster
500mg
$ 660.00

Medical Isotopes, Inc.
(Z)-2-[2-(Tritylamino)thiazol-4-yl]-2-(trityloxyimino)aceticAcidEthylEster
1 g
$ 1475.00

Total 4 raw suppliers

Chemical Property of (Z)-2-[2-(TritylaMino)thiazol-4-yl]-2-(trityloxyiMino)acetic Acid Ethyl Ester

Chemical Property:

Solubility.:DCM, Ethyl Acetate

Purity/Quality:

≥95% ^*data from raw suppliers

(Z)-2-[2-(Tritylamino)thiazol-4-yl]-2-(trityloxyimino)aceticAcidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (Z)-2-[2-(Tritylamino)thiazol-4-yl]-2-(trityloxyimino)acetic Acid Ethyl Ester is an intermediate in the synthesis of Cefdinir (C242670).

Technology Process of (Z)-2-[2-(TritylaMino)thiazol-4-yl]-2-(trityloxyiMino)acetic Acid Ethyl Ester

There total 5 articles about (Z)-2-[2-(TritylaMino)thiazol-4-yl]-2-(trityloxyiMino)acetic Acid Ethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.2%

: 76-83-5
trityl chloride

: 64485-82-1
(Z)-ethyl 2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetate

: 69689-86-7
ethyl 2-(2-tritylaminothiazol-4-yl)-(Z)-2-(tritylhydroxyimino)acetate

Guidance literature:: (Z)-ethyl 2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetate; With triethylamine; In acetonitrile; at 20 - 25 ℃; for 0.166667h;

trityl chloride; In acetonitrile; at 55 - 60 ℃; for 1h;

Reference yield:

: 66338-95-2
ethyl 4-chloro-2-hydroxyimino-3-oxo-butyrate

: 69689-86-7
ethyl 2-(2-tritylaminothiazol-4-yl)-(Z)-2-(tritylhydroxyimino)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 8.9 g / N,N-dimethyl-acetamide / 3 h / 20 °C

2: 52.2 percent / TEA / CHCl₃ / 1.5 h / 20 °C

With TEA; In chloroform; N,N-dimethyl acetamide;
DOI:10.1016/S0014-827X(03)00063-6

Reference yield:

: 66508-93-8
ethyl 2-(hydroxyimino)-3-oxybutyrate

: 69689-86-7
ethyl 2-(2-tritylaminothiazol-4-yl)-(Z)-2-(tritylhydroxyimino)acetate

Guidance literature:: Multi-step reaction with 3 steps

1: SO₂Cl₂; glac. AcOH / 1 h / 58 - 60 °C

2: 8.9 g / N,N-dimethyl-acetamide / 3 h / 20 °C

3: 52.2 percent / TEA / CHCl₃ / 1.5 h / 20 °C

With sulfuryl dichloride; TEA; acetic acid; In chloroform; N,N-dimethyl acetamide;
DOI:10.1016/S0014-827X(03)00063-6