Technology Process of 16-(N-Boc-S-trityl-cysteinylamido)hexadecanoic acid
There total 5 articles about 16-(N-Boc-S-trityl-cysteinylamido)hexadecanoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
ethyl 16-(N-Boc-S-trityl-cysteinylamido)hexadecanoate;
With
potassium hydroxide;
In
methanol; water;
at 20 ℃;
for 48h;
With
hydrogenchloride;
In
water;
pH=3;
DOI:10.1002/jlcr.1836
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sulfuric acid / Reflux
2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 - 20 °C
3.1: potassium hydroxide / methanol; water / 48 h / 20 °C
3.2: pH 3
With
sulfuric acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; potassium hydroxide;
In
methanol; dichloromethane; water;
DOI:10.1002/jlcr.1836
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: hydrazine hydrate / ethanol / 3 h / Reflux
1.2: Reflux
2.1: sulfuric acid / Reflux
3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 - 20 °C
4.1: potassium hydroxide / methanol; water / 48 h / 20 °C
4.2: pH 3
With
sulfuric acid; hydrazine hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; potassium hydroxide;
In
methanol; ethanol; dichloromethane; water;
DOI:10.1002/jlcr.1836
