1-Boc-3-(4-trifluoromethyl-phenylamino)-pyrrolidine

Base Information

Chemical Name:1-Boc-3-(4-trifluoromethyl-phenylamino)-pyrrolidine
CAS No.:816468-48-1
Molecular Formula:C₁₆H₂₁F₃N₂O₂
Molecular Weight:330.35
Hs Code.:2933990090
DSSTox Substance ID:DTXSID10461421
Mol file:816468-48-1.mol

Synonyms:816468-48-1;1-BOC-3-(4-TRIFLUOROMETHYL-PHENYLAMINO)-PYRROLIDINE;tert-Butyl 3-((4-(trifluoromethyl)phenyl)amino)pyrrolidine-1-carboxylate;tert-butyl 3-[4-(trifluoromethyl)anilino]pyrrolidine-1-carboxylate;TERT-BUTYL 3-{[4-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRROLIDINE-1-CARBOXYLATE;C16H21F3N2O2;DTXSID10461421;VCCRMYAKJBZXMI-UHFFFAOYSA-N;AKOS024260747;SB38862;1-boc-3-(4-trifluoromethylphenylamino)pyrrolidine;tert-Butyl3-((4-(trifluoromethyl)phenyl)amino)pyrrolidine-1-carboxylate

Suppliers and Price of 1-Boc-3-(4-trifluoromethyl-phenylamino)-pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
tert-Butyl 3-{[4-(trifluoromethyl)phenyl]amino}pyrrolidine-1-carboxylate 97%
1 g
$ 934.00

SynQuest Laboratories
tert-Butyl 3-{[4-(trifluoromethyl)phenyl]amino}pyrrolidine-1-carboxylate 97%
250 mg
$ 343.00

Labseeker
1-Boc-3-(4-Trifluoromethyl-phenylamino)-pyrrolidine 95
25g
$ 3300.00

J&W Pharmlab
1-Boc-3-(4-trifluoromethyl-phenylamino)-pyrrolidine 98%
5g
$ 4990.00

J&W Pharmlab
1-Boc-3-(4-trifluoromethyl-phenylamino)-pyrrolidine 98%
1g
$ 1560.00

J&W Pharmlab
1-Boc-3-(4-trifluoromethyl-phenylamino)-pyrrolidine 98%
500mg
$ 830.00

Crysdot
tert-Butyl3-((4-(trifluoromethyl)phenyl)amino)pyrrolidine-1-carboxylate 95+%
1g
$ 491.00

Chemenu
1-Boc-3-(4-trifluoromethyl-phenylamino)-pyrrolidine 95%
1g
$ 464.00

American Custom Chemicals Corporation
1-BOC-3-(4-TRIFLUOROMETHYL-PHENYLAMINO)-PYRROLIDINE 95.00%
5MG
$ 500.16

Alichem
tert-Butyl3-((4-(trifluoromethyl)phenyl)amino)pyrrolidine-1-carboxylate
1g
$ 441.10

Total 5 raw suppliers

Chemical Property of 1-Boc-3-(4-trifluoromethyl-phenylamino)-pyrrolidine

Chemical Property:

PSA：41.57000
LogP:4.13760
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:330.15551240
Heavy Atom Count:23
Complexity:413

Purity/Quality:

97%+ ^*data from raw suppliers

tert-Butyl 3-{[4-(trifluoromethyl)phenyl]amino}pyrrolidine-1-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(C1)NC2=CC=C(C=C2)C(F)(F)F

Technology Process of 1-Boc-3-(4-trifluoromethyl-phenylamino)-pyrrolidine

There total 1 articles about 1-Boc-3-(4-trifluoromethyl-phenylamino)-pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 402-43-7
p-trifluoromethylphenyl bromide

: 186550-13-0
3-amino-1-(t-butoxycarbonyl)pyrrolidine

: 816468-48-1
1-(tert-butoxycarbonyl)-3-(4-(trifluoromethyl)phenylamino)pyrrolidine

Guidance literature:: With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; In toluene; at 100 ℃; for 24h;
DOI:10.1021/jo0487193