cis-1-(4-Methoxyphenyl)-3-(2-propenyl)-4-benzoyl-2-azetidinone

Base Information

• Chemical Name: cis-1-(4-Methoxyphenyl)-3-(2-propenyl)-4-benzoyl-2-azetidinone
• CAS No.: 131533-56-7
• Molecular Formula: C₂₀H₁₉NO₃
• Molecular Weight: 321.376
• Mol file: 131533-56-7.mol

Synonyms:cis-1-(4-Methoxyphenyl)-3-(2-propenyl)-4-benzoyl-2-azetidinone

Chemical Property of cis-1-(4-Methoxyphenyl)-3-(2-propenyl)-4-benzoyl-2-azetidinone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-1-(4-Methoxyphenyl)-3-(2-propenyl)-4-benzoyl-2-azetidinone

There total 2 articles about cis-1-(4-Methoxyphenyl)-3-(2-propenyl)-4-benzoyl-2-azetidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3,3-Dimethylacryloyl chloride (3350-78-5) + 2-(4-methoxyphenylimino)-1-phenylethanone (113628-33-4,62558-62-7) → cis-1-(4-Methoxyphenyl)-3-(2-propenyl)-4-benzoyl-2-azetidinone (131533-56-7)

Guidance literature:

With triethylamine; In dichloromethane; for 14h; Heating;

DOI:10.1016/S0040-4039(00)97082-5

Reference yield: 38.0%

diethyl 2-methyl-2-propenyl phosphate (5458-10-6) + carbon monoxide (201230-82-2) + (E)-2-((4-methoxyphenyl)imino)-1-phenylethanone (62558-62-7,113628-33-4) → cis-1-(4-Methoxyphenyl)-3-(2-propenyl)-4-benzoyl-2-azetidinone (131533-56-7)

Guidance literature:

With N-Methyldicyclohexylamine; triphenylphosphine; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In tetrahydrofuran; for 5h; under 22065.2 Torr; Ambient temperature;

DOI:10.1021/jo00090a023

Reference yield: 100.0%

cis-1-(4-Methoxyphenyl)-3-(2-propenyl)-4-benzoyl-2-azetidinone (131533-56-7) → 4-Benzoyl-3-isopropylidene-1-(4-methoxy-phenyl)-azetidin-2-one (131533-57-8)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In benzene; for 6h; Heating;

DOI:10.1016/S0040-4039(00)97082-5

upstream raw materials:

3,3-Dimethylacryloyl chloride

2-(4-methoxyphenylimino)-1-phenylethanone

diethyl 2-methyl-2-propenyl phosphate

carbon monoxide

Downstream raw materials:

4-Benzoyl-3-isopropylidene-1-(4-methoxy-phenyl)-azetidin-2-one