(S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid

Base Information

Chemical Name:(S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid
CAS No.:811842-25-8
Molecular Formula:C₇H₁₃NO₃
Molecular Weight:159.185
Hs Code.:2932990090
DSSTox Substance ID:DTXSID30363716
Mol file:811842-25-8.mol

Synonyms:811842-25-8;(S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid;L-4'-Tetrahydropyranylglycine;(2S)-2-amino-2-(oxan-4-yl)acetic acid;(L)-4'-Tetrahydropyranylglycine;(2S)-2-amino-2-tetrahydropyran-4-yl-acetic acid;(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid;MFCD03419267;(S)-2-(Tetrahydro-pyran-4-yl)-glycine;SCHEMBL205456;DTXSID30363716;CS-D0014;HY-20838B;AKOS016842383;AC-30976;DS-12943;EN300-67313;(S)-amino-(tetrahydro-pyran-4-yl)-acetic acid;(S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)aceticacid

Suppliers and Price of (S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)aceticacid
50mg
$ 155.00

Crysdot
(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)aceticacid 97%
100mg
$ 87.00

Crysdot
(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)aceticacid 97%
250mg
$ 139.00

Crysdot
(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)aceticacid 97%
1g
$ 347.00

Crysdot
(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)aceticacid 97%
5g
$ 1419.00

Chemenu
(S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)aceticacid 97%
5g
$ 1337.00

Chemenu
(S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)aceticacid 97%
1g
$ 327.00

Biosynth Carbosynth
(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid
1 g
$ 652.00

Biosynth Carbosynth
(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid
250 mg
$ 215.00

Biosynth Carbosynth
(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid
100 mg
$ 108.00

Total 36 raw suppliers

Chemical Property of (S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid

Chemical Property:

Vapor Pressure:8.62E-05mmHg at 25°C
Refractive Index:1.505
Boiling Point:316.7 °C at 760 mmHg
PKA:2.25±0.10(Predicted)
Flash Point:145.3 °C
PSA：72.55000
Density:1.211 g/cm³
LogP:0.52520
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:-2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:159.08954328
Heavy Atom Count:11
Complexity:143

Purity/Quality:

97% ^*data from raw suppliers

(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)aceticacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCC1C(C(=O)O)N
Isomeric SMILES:C1COCCC1[C@@H](C(=O)O)N

Technology Process of (S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid

There total 4 articles about (S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₇H₉O₄^(1-)*Na⁽¹⁺⁾

: 811842-25-8,475649-32-2
(S)-2-amino-2-(tetrahydro-2 H-pyran-4-yl)acetic acid

Guidance literature:: With formate dehydrogenase; leucine dehydrogenase; ammonia; ammonium formate; nicotinamide adenine dinucleotide; In water; at 30 ℃; pH=8-8.5; enantioselective reaction; Enzymatic reaction;

Reference yield:

: 5337-03-1
tetrahydro-2H-pyran-4-carboxylic acid

: 811842-25-8,475649-32-2
(S)-2-amino-2-(tetrahydro-2 H-pyran-4-yl)acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: isopropylmagnesium chloride / tetrahydrofuran / 1.5 h / -10 - 0 °C

1.2: 2 h / Reflux

1.3: 1 h / -30 - 20 °C

2.1: water; potassium hydroxide; dipotassium hydrogenphosphate / methanol / 1 h / 20 °C

3.1: sodium methylate / isopropyl alcohol / 0.08 h / Cooling with ice

4.1: formate dehydrogenase; nicotinamide adenine dinucleotide; ammonia; ammonium formate; leucine dehydrogenase / water / 30 °C / pH 8-8.5 / Enzymatic reaction

With dipotassium hydrogenphosphate; formate dehydrogenase; leucine dehydrogenase; ammonia; water; isopropylmagnesium chloride; ammonium formate; sodium methylate; nicotinamide adenine dinucleotide; potassium hydroxide; In tetrahydrofuran; methanol; water; isopropyl alcohol;

Reference yield:

: 861160-58-9
C₉H₁₄O₄

: 811842-25-8,475649-32-2
(S)-2-amino-2-(tetrahydro-2 H-pyran-4-yl)acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: water; potassium hydroxide; dipotassium hydrogenphosphate / methanol / 1 h / 20 °C

2: sodium methylate / isopropyl alcohol / 0.08 h / Cooling with ice

3: formate dehydrogenase; nicotinamide adenine dinucleotide; ammonia; ammonium formate; leucine dehydrogenase / water / 30 °C / pH 8-8.5 / Enzymatic reaction

With dipotassium hydrogenphosphate; formate dehydrogenase; leucine dehydrogenase; ammonia; water; ammonium formate; sodium methylate; nicotinamide adenine dinucleotide; potassium hydroxide; In methanol; water; isopropyl alcohol;