(5S,6R)-6-(4-fluorophenyl)-6-(6-fluoro-3-pyridyl)-5-methyl-3-morpholinone

Base Information

Chemical Name:(5S,6R)-6-(4-fluorophenyl)-6-(6-fluoro-3-pyridyl)-5-methyl-3-morpholinone
CAS No.:1158972-08-7
Molecular Formula:C₁₆H₁₄F₂N₂O₂
Molecular Weight:304.296
Hs Code.:

Synonyms:(5S,6R)-6-(4-fluorophenyl)-6-(6-fluoro-3-pyridyl)-5-methyl-3-morpholinone

Suppliers and Price of (5S,6R)-6-(4-fluorophenyl)-6-(6-fluoro-3-pyridyl)-5-methyl-3-morpholinone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (5S,6R)-6-(4-fluorophenyl)-6-(6-fluoro-3-pyridyl)-5-methyl-3-morpholinone

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Technology Process of (5S,6R)-6-(4-fluorophenyl)-6-(6-fluoro-3-pyridyl)-5-methyl-3-morpholinone

There total 1 articles about (5S,6R)-6-(4-fluorophenyl)-6-(6-fluoro-3-pyridyl)-5-methyl-3-morpholinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 1158971-82-4
(1R,2S)-2-amino-1-(4-fluorophenyl)-1-(6-fluoro-3-pyridyl)-1-propanol

: 79-04-9
chloroacetyl chloride

: 1158972-08-7
(5S,6R)-6-(4-fluorophenyl)-6-(6-fluoro-3-pyridyl)-5-methyl-3-morpholinone

Guidance literature:: (1R,2S)-2-amino-1-(4-fluorophenyl)-1-(6-fluoro-3-pyridyl)-1-propanol; chloroacetyl chloride; With triethylamine; In chloroform; at 0 - 20 ℃;

With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃;
DOI:10.1021/jm900110t