4-methyl-4'-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]-nicotinanilide monohydrochloride

Base Information

Chemical Name:4-methyl-4'-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]-nicotinanilide monohydrochloride
CAS No.:292610-93-6
Molecular Formula:C₁₈H₁₂F₆N₄O
Molecular Weight:414.31
Hs Code.:

Synonyms:4-methyl-4'-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]-nicotinanilide monohydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-methyl-4'-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]-nicotinanilide monohydrochloride

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Technology Process of 4-methyl-4'-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]-nicotinanilide monohydrochloride

There total 1 articles about 4-methyl-4'-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]-nicotinanilide monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 94015-05-1
4-methylpyridine-3-carboxylic acid hydrochloride

: 123066-64-8
4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl] aniline

: 292610-93-6
4-methyl-4'-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]-nicotinanilide monohydrochloride

Guidance literature:: 4-methylpyridine-3-carboxylic acid hydrochloride; With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 3h;

4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl] aniline; In N,N-dimethyl-formamide; at 20 ℃; for 144h;
DOI:10.1016/j.bmc.2008.09.047