Benzenepropanoic acid, 2-methyl-alpha-2-propenyl-, methyl ester, (alphaR)- (9CI)

Base Information

• Chemical Name: Benzenepropanoic acid, 2-methyl-alpha-2-propenyl-, methyl ester, (alphaR)- (9CI)
• CAS No.: 808765-71-1
• Molecular Formula: C₁₄H₁₈O₂
• Molecular Weight: 218.296
• Mol file: 808765-71-1.mol

Synonyms:Benzenepropanoicacid, 2-methyl-a-2-propenyl-,methyl ester, (aR)-(9CI)

Chemical Property of Benzenepropanoic acid, 2-methyl-alpha-2-propenyl-, methyl ester, (alphaR)- (9CI)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenepropanoic acid, 2-methyl-alpha-2-propenyl-, methyl ester, (alphaR)- (9CI)

There total 4 articles about Benzenepropanoic acid, 2-methyl-alpha-2-propenyl-, methyl ester, (alphaR)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

allyl alcohol (107-18-6) → (+)-(S)-allyl 2-allyl-3-(2-methylphenyl)propionate (808765-71-1) + (-)-(R)-methyl 2-allyl-3-(2-methylphenyl)propionate (808765-71-1) + (2S,3S)-methyl 2-allyl-3-hydroxy-3-(2-methylphenyl)propionate + (-)-(2R,3S)-methyl 2-allyl-3-hydroxy-3-(2-methylphenyl)propionate

Guidance literature:

allyl alcohol; (-)-(R)-pentacarbonyl[(methoxy)(2-(tricarbonylchromium-2-methylphenyl)ethenyl)carbene]chromium⁽⁰⁾; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.0833333h;

With air; In diethyl ether; ethyl acetate; Title compound not separated from byproducts; Irradiation;

DOI:10.1021/ol048171m

Reference yield:

allyl alcohol (107-18-6) → (+)-(S)-allyl 2-allyl-3-(2-methylphenyl)propionate (808765-71-1) + (-)-(R)-methyl 2-allyl-3-(2-methylphenyl)propionate (808765-71-1) + (2S,3S)-methyl 2-allyl-3-hydroxy-3-(2-methylphenyl)propionate + (-)-(2R,3S)-methyl 2-allyl-3-hydroxy-3-(2-methylphenyl)propionate

Guidance literature:

allyl alcohol; (-)-(R)-pentacarbonyl[(methoxy)(2-(tricarbonylchromium-2-methylphenyl)ethenyl)carbene]chromium⁽⁰⁾; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.0833333h;

With air; In diethyl ether; ethyl acetate; Title compound not separated from byproducts; Irradiation;

DOI:10.1021/ol048171m

Reference yield:

allyl alcohol (107-18-6) → (+)-(S)-allyl 2-allyl-3-(2-methylphenyl)propionate (808765-71-1) + (-)-(R)-methyl 2-allyl-3-(2-methylphenyl)propionate (808765-71-1) + (2S,3S)-methyl 2-allyl-3-hydroxy-3-(2-methylphenyl)propionate + (-)-(2R,3S)-methyl 2-allyl-3-hydroxy-3-(2-methylphenyl)propionate

Guidance literature:

allyl alcohol; (R)-(methoxy)((E)-2-(2-methylphenyl)ethenyl)C=Cr(CO)5 tricarbonylchromium complex; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 1.5h;

In diethyl ether; Title compound not separated from byproducts; Irradiation;

DOI:10.1016/j.tet.2005.10.036

upstream raw materials:

allyl alcohol