4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-di-2-propenyl-1H-purine-8-yl)benzenesulfonic acid

Base Information

• Chemical Name: 4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-di-2-propenyl-1H-purine-8-yl)benzenesulfonic acid
• CAS No.: 96445-32-8
• Molecular Formula: C₁₇H₁₆N₄O₅S
• Molecular Weight: 388.404
• Mol file: 96445-32-8.mol

Synonyms:4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-di-2-propenyl-1H-purine-8-yl)benzenesulfonic acid

Chemical Property of 4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-di-2-propenyl-1H-purine-8-yl)benzenesulfonic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-di-2-propenyl-1H-purine-8-yl)benzenesulfonic acid

There total 4 articles about 4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-di-2-propenyl-1H-purine-8-yl)benzenesulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-sulfobenzoic acid monopotassium salt + EDAC [ethyl-dimethylaminopropylcarbodiimide] + 1,3-diallyl-6-amino-5-nitrosouracil (102284-73-1) → 4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-di-2-propenyl-1H-purine-8-yl)benzenesulfonic acid (96445-32-8)

Guidance literature:

With hydrogenchloride; potassium hydroxide; In ammonium hydroxide; water;

Reference yield:

p-N,N-dimethylaminobenzoic acid (619-84-1) → 4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-di-2-propenyl-1H-purine-8-yl)benzenesulfonic acid (96445-32-8)

Guidance literature:

Multi-step reaction with 2 steps

1: ethyl <3-(dimethylamino)propyl>carbodiimide (EDAC) / H₂O

2: 30percent aq. KOH / 0.17 h / Heating

With potassium hydroxide; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In water;

DOI:10.1021/jm00146a016

Reference yield:

1,3-diallyl-5,6-diaminouracil (102284-74-2) → 4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-di-2-propenyl-1H-purine-8-yl)benzenesulfonic acid (96445-32-8)

Guidance literature:

Multi-step reaction with 2 steps

1: ethyl <3-(dimethylamino)propyl>carbodiimide (EDAC) / H₂O

2: 30percent aq. KOH / 0.17 h / Heating

With potassium hydroxide; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In water;

DOI:10.1021/jm00146a016

upstream raw materials:

p-N,N-dimethylaminobenzoic acid

1,3-diallyl-5,6-diaminouracil

1,3-diallyl-6-amino-5-nitrosouracil

Downstream raw materials:

N-[3-(dimethylamino)propyl]-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-di-2-propenyl-1H-purine-8-yl)benzenesulfonamide