(1R,2S,3R)-3-hydrazinylcyclohex-4-ene-1,2-diol hydrochloride

Base Information

• Chemical Name: (1R,2S,3R)-3-hydrazinylcyclohex-4-ene-1,2-diol hydrochloride
• CAS No.: 1161437-11-1
• Molecular Formula: C₆H₁₂N₂O₂*ClH
• Molecular Weight: 180.634
• Mol file: 1161437-11-1.mol

Synonyms:(1R,2S,3R)-3-hydrazinylcyclohex-4-ene-1,2-diol hydrochloride

Chemical Property of (1R,2S,3R)-3-hydrazinylcyclohex-4-ene-1,2-diol hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,2S,3R)-3-hydrazinylcyclohex-4-ene-1,2-diol hydrochloride

There total 1 articles about (1R,2S,3R)-3-hydrazinylcyclohex-4-ene-1,2-diol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

di-tert-butyl 1-((1R,5R,6S)-5,6-dihydroxycyclohex-2-enyl)hydrazine-1,2-dicarboxylate (1161437-09-7) → (1R,2S,3R)-3-hydrazinylcyclohex-4-ene-1,2-diol hydrochloride (1161437-11-1)

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 0 - 20 ℃;

DOI:10.1021/ol900779v

Reference yield: 100.0%

(1R,2S,3R)-3-hydrazinylcyclohex-4-ene-1,2-diol hydrochloride (1161437-11-1) → (1R,2S,3R)-3-aminocyclohexane-1,2-diol hydrochloride (1161437-13-3)

Guidance literature:

With platinum(IV) oxide; hydrogen; In methanol; at 20 ℃; for 48h; optical yield given as %ee;

DOI:10.1021/ol900779v

Reference yield: 75.0%

(1R,2S,3R)-3-hydrazinylcyclohex-4-ene-1,2-diol hydrochloride (1161437-11-1) → (1R,2S)-1,2-dihydroxycyclohexa-3-ene (170211-25-3)

Guidance literature:

With water; potassium carbonate; potassium hexacyanoferrate(III); In tetrahydrofuran; at 20 ℃; for 0.333333h; optical yield given as %ee;

DOI:10.1021/ol900779v

upstream raw materials:

di-tert-butyl 1-((1R,5R,6S)-5,6-dihydroxycyclohex-2-enyl)hydrazine-1,2-dicarboxylate

Downstream raw materials:

(1R,2S,3R)-3-aminocyclohexane-1,2-diol hydrochloride

(1R,2S)-1,2-dihydroxycyclohexa-3-ene