Technology Process of (R)-2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethylamine
There total 9 articles about (R)-2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethylamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrazine hydrate;
In
ethanol;
Heating;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 89 percent / potassium carbonate / dimethylformamide / 15 h / 80 °C
2: 1.) O3, 2.) sodium borohydride / 1.) CH3OH, CH2Cl2, -74 deg C, 35 min, 2.) water, -74 deg C, r.t.
3: 95 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 0 °C
4: 93 percent / 90percent hydrazine hydrate / ethanol / Heating
With
sodium tetrahydroborate; potassium carbonate; ozone; hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 48 percent / triphenylphosphine, di-isopropyl azodicarboxylate / tetrahydrofuran / 2 h / 0 °C
2: 76 percent / N,N-dimethylaniline / 0.33 h / Heating
3: 89 percent / potassium carbonate / dimethylformamide / 15 h / 80 °C
4: 1.) O3, 2.) sodium borohydride / 1.) CH3OH, CH2Cl2, -74 deg C, 35 min, 2.) water, -74 deg C, r.t.
5: 95 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 0 °C
6: 93 percent / 90percent hydrazine hydrate / ethanol / Heating
With
sodium tetrahydroborate; di-isopropyl azodicarboxylate; potassium carbonate; ozone; hydrazine hydrate; N,N-dimethyl-aniline; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide;
