Boc-Gln-Lys-OMe

Base Information

• Chemical Name: Boc-Gln-Lys-OMe
• CAS No.: 73995-28-5
• Molecular Formula: C₂₅H₃₇ClN₄O₈
• Molecular Weight: 557.044

Synonyms:Boc-Gln-Lys-OMe

Chemical Property of Boc-Gln-Lys-OMe

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Boc-Gln-Lys-OMe

There total 2 articles about Boc-Gln-Lys-OMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.6%

Boc-Gln-ONp (15387-45-8) + H-Lys-OMe*HCl (73995-27-4) → Boc-Gln-Lys-OMe (73995-28-5)

Guidance literature:

With TEA; In N,N-dimethyl-formamide; for 24h; Ambient temperature;

DOI:10.1246/bcsj.53.192

Reference yield:

Nε-(2-Chlorophenylmethoxycarbonyl)-(S)-lysine (42390-97-6,201014-19-9) → Boc-Gln-Lys-OMe (73995-28-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 70.6 percent / thionyl chloride / 72 h / Ambient temperature

2: 83.6 percent / 1.) TEA / dimethylformamide / 24 h / Ambient temperature

With thionyl chloride; TEA; In N,N-dimethyl-formamide;

DOI:10.1246/bcsj.53.192

Reference yield:

Boc-Gln-Lys-OMe (73995-28-5) → Boc-Pro-Pro-Gln-Lys-OMe (73995-31-0)

Guidance literature:

Multi-step reaction with 2 steps

1: TFA / 0.67 h / Ambient temperature

2: 1.) TEA / tetrahydrofuran / 72 h / Ambient temperature

With TEA; trifluoroacetic acid; In tetrahydrofuran;

DOI:10.1246/bcsj.53.192

upstream raw materials:

Boc-Gln-ONp

H-Lys-OMe*HCl

N^ε-(2-Chlorophenylmethoxycarbonyl)-(S)-lysine

Downstream raw materials:

(S)-2-((S)-2-Amino-4-carbamoyl-butyrylamino)-6-(2-chloro-benzyloxycarbonylamino)-hexanoic acid methyl ester

(S)-2-((S)-4-Carbamoyl-2-{[(S)-1-((S)-pyrrolidine-2-carbonyl)-pyrrolidine-2-carbonyl]-amino}-butyrylamino)-6-(2-chloro-benzyloxycarbonylamino)-hexanoic acid methyl ester

Boc-Pro-Pro-Gln-Lys-OMe

Boc-Leu-Glu(OBu^t)-Gly-Pro-Pro-Gln-Lys-OMe

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 73995-28-5 Boc-Gln-Lys-OMe

Send

Send

Metric Ton KG G Pound L ML

Send

Send